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Postoperative administration of the acetylcholinesterase inhibitor, donepezil, interferes with bone healing and implant osseointegration in a rat model
(
MDPI AG
, 2020 , Article)
Donepezil is an acetylcholinesterase inhibitor commonly used to treat mild to moderate Alzheimer?s disease. Its use has been associated with increased bone mass in humans and animals. However, the effect of postoperative ...
Composition and characteristics of trabecular bone in osteoporosis and osteoarthritis
(
Elsevier Inc.
, 2020 , Article)
Background
Bone strength depends on multiple factors such as bone density, architecture and composition turnover. However, the role these factors play in osteoporotic fractures is not well understood.
Purpose
The aim ...
COVID-19 infection localization and severity grading from chest X-ray images
(
Elsevier Ltd
, 2021 , Article)
The immense spread of coronavirus disease 2019 (COVID-19) has left healthcare systems incapable to diagnose and test patients at the required rate. Given the effects of COVID-19 on pulmonary tissues, chest radiographic ...
Efficacy of aerosol reduction measures for dental aerosol generating procedures
(
Taylor and Francis Ltd.
, 2022 , Article)
Aerosol particles generated by dental procedures could facilitate the transmission of infectious diseases and contain carcinogen particles. Such particles can penetrate common surgical masks and reach the lungs, leading ...
Detection and severity classification of COVID-19 in CT images using deep learning
(
MDPI
, 2021 , Article)
Detecting COVID-19 at an early stage is essential to reduce the mortality risk of the patients. In this study, a cascaded system is proposed to segment the lung, detect, localize, and quantify COVID-19 infections from ...
Is there truly an increase in risk of cardiovascular and hematological adverse events with vascular endothelial growth factor receptor tyrosine kinase inhibitors?
(
Taylor and Francis Ltd
, 2020 , Article)
Objectives: Recent studies have shown an increase risk of cardiovascular and hematological adverse events associated with vascular endothelial growth factor tyrosine kinase inhibitors (VEGF-TKIs). The authors hypothesize ...
Patient-Specific Seizure Detection Using Nonlinear Dynamics and Nullclines
(
Institute of Electrical and Electronics Engineers Inc.
, 2020 , Article)
Nonlinear dynamics has recently been extensively used to study epilepsy due to the complex nature of the neuronal systems. This study presents a novel method that characterizes the dynamic behavior of pediatric seizure ...
Mortality prediction utilizing blood biomarkers to predict the severity of COVID-19 using machine learning technique
(
MDPI
, 2021 , Article)
Healthcare researchers have been working on mortality prediction for COVID-19 patients with differing levels of severity. A rapid and reliable clinical evaluation of disease intensity will assist in the allocation and ...
Acetylcholinesterase inhibitors and risk of bleeding and acute ischemic events in non-hypertensive Alzheimer's patients
(
John Wiley and Sons Inc
, 2021 , Article)
Introduction
Acetylcholinesterase inhibitors (AChEIs) are commonly used to treat mild to moderate cases of Alzheimer disease (AD). To the best of our knowledge, there has been no study estimating the risk of bleeding and ...
Core outcomes in gestational diabetes for treatment trials: The Gestational Metabolic Group treatment set
(
John Wiley and Sons Inc
, 2021 , Article)
Aims
With the rising number of outcomes being reported following gestational diabetes (GDM), the outcomes in existing studies vary widely making it challenging to compare and contrast the effectiveness of different ...