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السجلات المعروضة 51 -- 60 من 193
Direct cardiovascular impact of SGLT2 inhibitors: mechanisms and effects
(
Springer New York LLC
, 2018 , Article Review)
Diabetes is a global epidemic and a leading cause of death with more than 422 million patients worldwide out of whom around 392 million alone suffer from type 2 diabetes (T2D). Sodium-glucose cotransporter 2 inhibitors ...
A Review of the Clinical Pharmacokinetics and Pharmacodynamics of Isavuconazole
(
Springer-Verlag France
, 2018 , Article Review)
Invasive fungal infections are a major cause of morbidity and mortality, especially for immunocompromised patients. Treatment options are few and most are limited by safety and formulation concerns. Isavuconazole is a new ...
Retinopathy of Type 1 Diabetes in Arab Countries: Systematic Review and Meta-Analysis.
(
Karger
, 2018 , Article Review)
To conduct a systematic review and meta-analysis of retinopathy prevalence in patients with type 1 diabetes (T1D) in 22 Arab countries. We systematically searched 4 different literature databases (PubMed, Science Direct, ...
The physiological effects of concurrent strength and endurance training sequence: A systematic review and meta-analysis.
(
Taylor & Francis
, 2017 , Article Review)
We conducted a systematic literature review and meta-analysis to assess the chronic effects of the sequence of concurrent strength and endurance training on selected important physiological and performance parameters, ...
Epidemic T2DM, early development and epigenetics: implications of the Chinese Famine.
(
Nature Research
, 2018 , Article Review)
The gene-environment interactions resulting from famine and the subsequent increased intergenerational risk of type 2 diabetes mellitus (T2DM) have contributed to the current epidemic of T2DM in China, which poses major ...
The Dual Specificity Role of Transcription Factor FOXO in Type 2-diabetes and Cancer
(
Bentham Science Publishers
, 2018 , Article Review)
The FOXO (Forkhead box O) transcription factors are implicated in several signaling pathways and play a vital role in various cellular and physiological processes include for instance, ROS (reactive oxygen species) response, ...
Design for sustainable manufacturing: Approach, implementation, and assessment
(
MDPI AG
, 2018 , Article Review)
The implementation of sustainable systems is an essential requirement in modern manufacturing, in order to minimize the environmental and health concerns, and conserves energy and natural resources. The sustainable ...
Effects of acute and chronic exercise on immunological parameters in the elderly aged: Can physical activity counteract the effects of aging?
(
Frontiers Media S.A.
, 2018 , Article Review)
Immunosenescence is characterized by deterioration of the immune system caused by aging which induces changes to innate and adaptive immunity. Immunosenescence affects function and phenotype of immune cells, such as ...
Metformin in pregnancy to avert gestational diabetes in women at high risk: Meta-analysis of randomized controlled trials.
(
Wiley
, 2019 , Article Review)
Previous randomized and observational studies on the efficacy of metformin in pregnancy to reduce incident gestational diabetes mellitus (GDM) in women at high risk (obesity, polycystic ovary syndrome [PCOS], or pregestational ...
Lichen planus: a comprehensive evidence-based analysis of medical treatment
(
Blackwell Publishing Ltd
, 2019 , Article Review)
Lichen planus (LP) is a chronic-relapsing inflammatory skin disease. Although many drugs have been used for the management of LP, some of them lack the backup by strong therapeutic evidence, while others are not suitable ...