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Stem cells based in vitro models: Trends and prospects in biomaterials cytotoxicity studies
(
IOP Publishing Ltd
, 2021 , Article)
Advanced biomaterials are increasingly used for numerous medical applications from the delivery of cancer-targeted therapeutics to the treatment of cardiovascular diseases. The issues of foreign body reactions induced by ...
Osteopontin: A Promising Therapeutic Target in Cardiac Fibrosis
(
NLM (Medline)
, 2019 , Article)
Osteopontin (OPN) is recognized for its significant roles in both physiological and pathological processes. Initially, OPN was recognized as a cytokine with pro-inflammatory actions. More recently, OPN has emerged as a ...
Evaluation of angiogenic potential of heparin and thyroxine releasing wound dressings
(
Taylor and Francis Ltd.
, 2021 , Article)
In the present research, heparin (1 ?g/ml, 5 ?g/ml) and thyroxine (1 ?g/ml, 5 ?g/ml) loaded wound dressings were prepared. Ultrastructure of the developed scaffolds revealed by scanning electron microscope and fourier ...
Development of biopolymeric hybrid scaffold-based on aac/go/nhap/tio2 nanocomposite for bone tissue engineering: In-vitro analysis
(
MDPI AG
, 2021 , Article)
Bone tissue engineering is an advanced field for treatment of fractured bones to re-store/regulate biological functions. Biopolymeric/bioceramic-based hybrid nanocomposite scaffolds are potential biomaterials for bone ...
p53 signaling in cancer progression and therapy
(
BioMed Central Ltd
, 2021 , Article)
The p53 protein is a transcription factor known as the "guardian of the genome" because of its critical function in preserving genomic integrity. The TP53 gene is mutated in approximately half of all human malignancies, ...
Gold Nanoparticle-Based Platforms for Diagnosis and Treatment of Myocardial Infarction
(
American Chemical Society
, 2020 , Article)
In recent years, an increasing rate of mortality due to myocardial infarction (MI) has led to the development of nanobased platforms, especially gold nanoparticles (AuNPs), as promising nanomaterials for diagnosis and ...
Light-Controlled Growth Factors Release on Tetrapodal ZnO-Incorporated 3D-Printed Hydrogels for Developing Smart Wound Scaffold
(
John Wiley and Sons Inc
, 2021 , Article)
Advanced wound scaffolds that integrate active substances to treat chronic wounds have gained significant recent attention. While wound scaffolds and advanced functionalities have previously been incorporated into one ...
Arabinoxylan/graphene-oxide/nHAp-NPs/PVA bionano composite scaffolds for fractured bone healing
(
John Wiley and Sons Ltd
, 2021 , Article)
The importance of bone scaffolds has increased many folds in the last few years; however, during bone implantation, bacterial infections compromise the implantation and tissue regeneration. This work is focused on this ...
Antimetastatic Activity of Lactoferrin-Coated Mesoporous Maghemite Nanoparticles in Breast Cancer Enabled by Combination Therapy
(
American Chemical Society
, 2020 , Article)
Despite successes in breast cancer treatment, the incidence of metastasis, drug resistance, and toxicity limit the efficacy of current therapeutic modalities. Herein, by designing lactoferrin-doxorubicin-mesoporous maghemite ...
Ferritin Nanocage Conjugated Hybrid Hydrogel for Tissue Engineering and Drug Delivery Applications
(
American Chemical Society
, 2020 , Article)
Hydrogels have recently been attractive in various drug delivery and tissue engineering applications because of their structural similarities to the natural extracellular matrix. Despite enormous advances in the application ...