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Efficacy and safety of selinexor for patients with relapsed and refractory multiple myeloma: A meta-analysis
(
Elsevier
, 2024 , Article)
PurposeSelinexor is a first-in-class, oral selective-inhibitor-of-nuclear-export, granted accelerated approval by FDA (2019) for relapsed and refractory multiple myeloma (RRMM). We sought to quantitatively summarize the ...
Bi-attention DoubleUNet: A deep learning approach for carotid artery segmentation in transverse view images for non-invasive stenosis diagnosis
(
Elsevier
, 2024 , Article)
The carotid artery is a vital blood vessel that supplies oxygenated blood to the brain. Blockages in this artery can lead to life-threatening illnesses, making accurate diagnosis essential. While ultrasound (US) imaging ...
Circadian Syndrome Is Associated with Dietary Patterns among Middle-Older Americans: The Health and Retirement Study
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2024 , Article)
Population aging is a global demographic characteristic of the 21st century, and healthy eating is a core component of healthy aging. However, limited evidence is available among older adults for associations between diet ...
Effectiveness of locally produced ready-to-use supplementary foods on the prevention of stunting in children aged 6-23 months: A community-based trial from Pakistan
(
Cambridge University Press
, 2023 , Article)
Undernutrition is a major public health problem in developing countries. Around 40·2 % of children are stunted in Pakistan. This longitudinal study aimed to assess the effectiveness of locally produced ready-to-use ...
BRCA1 and Its Vulnerable C-Terminal BRCT Domain: Structure, Function, Genetic Mutations and Links to Diagnosis and Treatment of Breast and Ovarian Cancer
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2024 , Article)
The BRCA1 is a tumor suppressor gene that encodes for the BRCA1 protein, which plays a vital role in DNA repair, cell cycle regulation, and the maintenance of genomic stability. The BRCA1 protein interacts with a variety ...
Exploring the role of oral microbiome dysbiosis in cardiometabolic syndrome and smoking
(
Taylor and Francis Ltd.
, 2024 , Article Review)
Oral microbiome research has gained significant interest in recent years due to its potential impact on overall health. Smoking has been identified as a significant modulator of the oral microbiome composition, leading to ...
Nrf-2-dependent antioxidant and anti-inflammatory effects underlie the protective effect of esculeoside A against retinal damage in streptozotocin-induced diabetic rats
(
Elsevier
, 2024 , Article)
Esculeoside A (ESA) is a tomato-derived glycoside with antioxidant and anti-inflammatory properties. The protective effect of ESA against diabetic retinopathy is not well-investigated and was the core objective of this ...
Cranial measurements obtained by three-dimensional computed tomography technique in the estimation of sex of contemporary Black South Africans
(
Elsevier
, 2024 , Article)
Human identification forms an integral part of forensic and biological anthropology. For proper identification, a biological profile made up of biodata such as age, sex, ancestry, antemortem stature, and factors of ...
2D magnesium phosphate resorbable coating to enhance cell adhesion on titanium surfaces
(2024 , Article)
Titanium and its alloys are essential metals for orthopedic implant manufacturing due to their exceptional mechanical properties and biocompatibility, used extensively for treating various orthopedic conditions. However, ...
Ether, sulfide and sulfone derivatives of cinnamaldehyde: Insights into synthesis, structural elucidation and solvatochromism
(
Elsevier
, 2024 , Article)
Symmetric ether, sulfide and sulfone derivatives based on Schiff base functionalized group (3a-c) were synthesized via classical condensation of 4,4′-diaminodiphenyl precursors (1a-c) and cinnamaldehyde (2) in methanol at ...