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Potential Adverse Effects of Resveratrol: A Literature Review.
(
MDPI
, 2020 , Article Review)
Due to its health benefits, resveratrol (RE) is one of the most researched natural polyphenols. Resveratrol's health benefits were first highlighted in the early 1990s in the French paradox study, which opened extensive ...
Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance.
(
BMC
, 2020 , Article Review)
Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients. The factors limiting the current screening approaches to leukemia ...
A service evaluation and stakeholder perspectives of an innovative digital minor illness referral service from NHS 111 to community pharmacy.
(
Public Library of Science
, 2020 , Article)
The management of minor conditions represents a significant burden for urgent and emergency care services and reduces the capacity to provide specialist care for higher acuity healthcare need. A pilot Digital Minor Illness ...
Risk of wheezing and asthma exacerbation in children treated with paracetamol versus ibuprofen: a systematic review and meta-analysis of randomised controlled trials
(
BMC
, 2020 , Article)
Background
Paracetamol and ibuprofen are the most commonly used medications for fever and pain management in children. While the efficacy appears similar with both drugs, there are contradictory findings related to adverse ...
High expression of immune checkpoints is associated with the TIL load, mutation rate and patient survival in colorectal cancer.
(
Spandidos Publications
, 2020 , Article)
Adoptive cell therapy with the use of tumor-infiltrating lymphocytes (TILs) is a very promising immunotherapeutic approach for the treatment of patients with colorectal cancer (CRC). However, within the tumor microenvironment, ...
Development and diagnostic validation of the Brisbane Evidence-Based Language Test.
(
Taylor & Francis
, 2020 , Article)
To describe the development and determine the diagnostic accuracy of the Brisbane Evidence-Based Language Test in detecting aphasia. Consecutive acute stroke admissions ( = 100; mean = 66.49y) participated in a single ...
Views and experiences of decision-makers on organisational safety culture and medication errors
(
Wiley
, 2020 , Article)
In 2017, the World Health Organization published “Medication Without Harm, WHO Global Patient Safety Challenge,” to reduce patient harm caused by unsafe medication use practices. While the five objectives emphasise the ...
Mutagenesis-Based Characterization and Improvement of a Novel Inclusion Body Tag
(
Frontiers Media
, 2020 , Article)
Whereas, bacterial inclusion bodies (IBs) for long were regarded as undesirable aggregates emerging during recombinant protein production, they currently receive attention as promising nanoparticulate biomaterials with ...
A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic.
(
BMC
, 2020 , Article)
Atypical Beijing genotype Mycobacterium tuberculosis strains are widespread in South Africa and have acquired resistance to up to 13 drugs on multiple occasions. It is puzzling that these strains have retained fitness and ...
High fractional excretion of glycation adducts is associated with subsequent early decline in renal function in type 1 diabetes
(
Nature Publishing Group
, 2020 , Article)
Increased protein glycation, oxidation and nitration is linked to the development of diabetic nephropathy. We reported levels of serum protein glycation, oxidation and nitration and related hydrolysis products, glycation, ...