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Association Between Serum Bicarbonate Levels and Prediabetes and Subclinical Inflammation in Young Healthy Adults: A Cross-sectional Study
(
Taylor and Francis Ltd.
, 2023 , Article)
Purpose: Low bicarbonate, a hallmark of metabolic acidosis is associated with various diseases. This study investigated associations between bicarbonate levels with prediabetes and subclinical inflammation among healthy ...
ApoM binds endotoxin contributing to neutralization and clearance by High Density Lipoprotein.
(
Elsevier
, 2023 , Article)
HDL possesses anti-inflammatory properties, however, the exact mechanism is not fully understood. Endotoxin is a potent inducers of TLR4 signaling, leading to inflammatory mediators' release. It has been estimated that ...
Ultrasound Intima-Media Complex (IMC) Segmentation Using Deep Learning Models
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
Common carotid intima-media thickness (CIMT) is a common measure of atherosclerosis, often assessed through carotid ultrasound images. However, the use of deep learning methods for medical image analysis, segmentation and ...
Editorial: Role of Iron in Bacterial Pathogenesis
(
Frontiers Media S.A.
, 2018 , Article)
Iron is the fourth-most abundant element on the earth, and it is needed by most organisms, including bacteria. It exists in two oxidation states, Fe2+ and Fe3+, and is involved in many oxido-reduction reactions (Andrews ...
High–temporal resolution profiling reveals distinct immune trajectories following the first and second doses of COVID-19 mRNA vaccines
(
American Association for the Advancement of Science
, 2022 , Article)
Knowledge of the mechanisms underpinning the development of protective immunity conferred by mRNA vaccines is fragmentary. Here, we investigated responses to coronavirus disease 2019 (COVID-19) mRNA vaccination via ...
An Adjuvanted Inactivated SARS-CoV-2 Microparticulate Vaccine Delivered Using Microneedles Induces a Robust Immune Response in Vaccinated Mice
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
SARS-CoV-2, the causal agent of COVID-19, is a contagious respiratory virus that frequently mutates, giving rise to variant strains and leading to reduced vaccine efficacy against the variants. Frequent vaccination against ...
Dynamics of Anti-S IgG Antibodies Titers after the Second Dose of COVID-19 Vaccines in the Manual and Craft Worker Population of Qatar
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
There is limited seroepidemiological evidence on the magnitude and long-term durability of antibody titers of mRNA and non-mRNA vaccines in the Qatari population. This study was conducted to generate evidence on long-term ...
Vitamin D status affects proteomic profile of HDL-associated proteins and inflammatory mediators in dyslipidemia
(
Elsevier
, 2024 , Article)
Vitamin D deficiency and dyslipidemia have substantial implications for human health globally. Vitamin D is essential for bone metabolism and immune modulation, and its insufficiency is linked to various chronic inflammatory ...
TB-CXRNet: Tuberculosis and Drug-Resistant Tuberculosis Detection Technique Using Chest X-ray Images
(
Springer Nature
, 2024 , Article)
Tuberculosis (TB) is a chronic infectious lung disease, which caused the death of about 1.5 million people in 2020 alone. Therefore, it is important to detect TB accurately at an early stage to prevent the infection and ...
Real-World Effectiveness of the Varicella Vaccine among Children and Adolescents in Qatar: A Case–Control Study
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
Background: Despite the availability of a highly efficacious vaccine, varicella outbreaks are still being reported globally. In this study, we evaluated the real-world effectiveness of varicella vaccination among children ...