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MDM2- an indispensable player in tumorigenesis
(
Springer Science and Business Media B.V.
, 2023 , Article Review)
Murine double minute 2 (MDM2) is a well-recognized molecule for its oncogenic potential. Since its identification, various cancer-promoting roles of MDM2 such as growth stimulation, sustained angiogenesis, metabolic ...
Motor Control Exercises Compared to Strengthening Exercises for Upper- And Lower-Extremity Musculoskeletal Disorders: A Systematic Review with Meta-Analyses of Randomized Controlled Trials
(
Oxford University Press
, 2021 , Article Review)
The purpose of this review was to compare the efficacy of motor control exercises (MCEs) to strengthening exercises for adults with upper- or lower-extremity musculoskeletal disorders (MSKDs). Methods: Electronic searches ...
Reactive oxygen species: Modulators of phenotypic switch of vascular smooth muscle cells
(
MDPI
, 2020 , Article Review)
Reactive oxygen species (ROS) are natural byproducts of oxygen metabolism in the cell. At physiological levels, they play a vital role in cell signaling. However, high ROS levels cause oxidative stress, which is implicated ...
Hybrid ejector-absorption refrigeration systems: A review
(
MDPI
, 2021 , Article Review)
Absorption Refrigeration Systems (ARS) are potential alternatives to direct expansion (DX) refrigeration systems. This review focused on the incorporation of an ejector into absorption refrigeration cycles to constitute ...
Prescribing patterns of antihypertensive medications: A systematic review of literature between 2010 and 2020
(
Elsevier
, 2023 , Article Review)
Background: Hypertension has affected over 1.13 billion people worldwide in 2015 and it's one of the most preventable risk-factors for morbidity and mortality. Antihypertensives significantly reduce cardiovascular risks. ...
Forging the Path to Precision Medicine in Qatar: A Public Health Perspective on Pharmacogenomics Initiatives
(
Frontiers Media
, 2024 , Article Review)
Pharmacogenomics (PGx) is an important component of precision medicine that promises tailored treatment approaches based on an individual’s genetic information. Exploring the initiatives in research that help to integrate ...
Ace2 is an adjacent element of atherosclerosis and covid-19 pathogenesis
(
MDPI
, 2021 , Article Review)
COVID-19 is a highly contagious new infection caused by the single-stranded RNA SarsCoV-2 virus. For the first time, this infection was recorded in December 2019 in the Chinese province of Wuhan. The virus presumably crossed ...
Accuracy of procalcitonin for diagnosing sepsis in adult patients admitted to the emergency department: a systematic review and meta-analysis
(
BioMed Central Ltd
, 2024 , Article Review)
Background
Differentiating sepsis from non-infectious systemic inflammatory response syndrome (SIRS) is challenging. Biomarkers like procalcitonin (PCT) aid early risk assessment and guide antibiotic use. This study aims ...
Current Technologies and Future Perspectives in Immunotherapy towards a Clinical Oncology Approach
(
MDPI
, 2024 , Article Review)
Immunotherapy is now established as a potent therapeutic paradigm engendering antitumor immune response against a wide range of malignancies and other diseases by modulating the immune system either through the stimulation ...
Pathophysiological Aspects of the Development of Abdominal Aortic Aneurysm with a Special Focus on Mitochondrial Dysfunction and Genetic Associations
(
De Gruyter Open Ltd
, 2021 , Article Review)
Abdominal aortic aneurysm (AAA) is a complex degenerative vascular disease, with considerable morbidity and mortality rates among the elderly population. The mortality of AAA is related to aneurysm expansion (the enlargement ...