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Current status of tissue engineering in the management of severe hypospadias
(
Frontiers Media S.A.
, 2018 , Article Review)
Hypospadias, characterized by misplacement of the urinary meatus in the lower side of the penis, is a frequent birth defect in male children. Because of the huge variation in the anatomic presentation of hypospadias, no ...
Hydrogels for Advanced Stem Cell Therapies: A Biomimetic Materials Approach for Enhancing Natural Tissue Function
(
Institute of Electrical and Electronics Engineers
, 2018 , Article)
Stem-cell-based therapy is a promising approach for the treatment of a myriad of diseases and injuries. However, the low rate of cell survival and the uncontrolled differentiation of the injected stem cells currently remain ...
Kidney-on-a-chip: untapped opportunities
(
Elsevier B.V.
, 2018 , Article Review)
The organs-on-a-chip technology has shown strong promise in mimicking the complexity of native tissues in vitro and ex vivo, and recently significant advances have been made in applying this technology to studies of the ...
In vitro models and systems for evaluating the dynamics of drug delivery to the healthy and diseased brain
(
Elsevier B.V.
, 2018 , Article Review)
The blood-brain barrier (BBB) plays a crucial role in maintaining brain homeostasis and transport of drugs to the brain. The conventional animal and Transwell BBB models along with emerging microfluidic-based BBB-on-chip ...
Novel electrospun chitosan/polyvinyl alcohol/zinc oxide nanofibrous mats with antibacterial and antioxidant properties for diabetic wound healing
(
Elsevier B.V.
, 2018 , Article)
Non-healing wound is a serious complication of diabetes, associated with extremely slow wound closure, and a high rate of infection, resulting in amputation or losses of limbs, high health care cost and poor quality of ...
Rheological and controlled release properties of hydrogels based on mushroom hyperbranched polysaccharide and xanthan gum
(
Elsevier B.V.
, 2018 , Article)
A hyperbranched polysaccharide, coded as TM3a, was extracted from the Pleurotus tuber-regium sclerotia. TM3a was hybridized with xanthan gum (XG) by chemical crosslinking using sodium trimetaphosphate (STMP) to obtain new ...