Search
Now showing items 1-10 of 10
Advances in osteobiologic materials for bone substitutes.
(
John Wiley and Sons
, 2018 , Article Review)
A significant challenge in the current orthopedics is the development of suitable osteobiologic materials that can replace the conventional allografts, autografts, and xenografts and thereby serve as implant materials as ...
Rapid diagnostics of coronavirus disease 2019 in early stages using nanobiosensors: Challenges and opportunities
(
Elsevier B.V.
, 2021 , Article Review)
The rapid outbreak of coronavirus disease 2019 (COVID-19) around the world is a tragic and shocking event that demonstrates the unpreparedness of humans to develop quick diagnostic platforms for novel infectious diseases. ...
Rapid Antibody-Based COVID-19 Mass Surveillance: Relevance, Challenges, and Prospects in a Pandemic and Post-Pandemic World.
(
MDPI
, 2020 , Article Review)
The aggressive outbreak of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) as COVID-19 (coronavirus disease-2019) pandemic demands rapid and simplified testing tools for its effective management. Increased ...
Carbon Nanotubes in Biomedical Applications: Factors, Mechanisms, and Remedies of Toxicity
(
American Chemical Society
, 2016 , Article Review)
Carbon nanotubes (CNTs) represent one of the most studied allotropes of carbon. The unique physicochemical properties of CNTs make them among prime candidates for numerous applications in biomedical fields including drug ...
Glioma extracellular vesicles for precision medicine: prognostic and theragnostic application
(
Springer
, 2022 , Article Review)
EV produced by tumour cells carry a diverse population of proteins, lipids, DNA, and RNA molecules throughout the body and appear to play an important role in the overall development of the disease state, according to ...
Chitosan-based electrospun nanofibers for diabetic foot ulcer management; recent advances
(
Elsevier
, 2023 , Article Review)
Diabetic foot ulcer (DFU) healing has long been a major medical challenge. The type of dressing is an essential factor in wound healing, prevention of local infection, and scar formation. Today, smart wound dressings or ...
Cancer immunotherapy with immune checkpoint inhibitors (ICIs): potential, mechanisms of resistance, and strategies for reinvigorating T cell responsiveness when resistance is acquired
(
BioMed Central Ltd
, 2023 , Article Review)
Cancer is still the leading cause of death globally. The approval of the therapeutic use of monoclonal antibodies against immune checkpoint molecules, notably those that target the proteins PD-1 and PD-L1, has changed the ...
Single-Cell RNA Sequencing with Spatial Transcriptomics of Cancer Tissues
(
MDPI
, 2022 , Article Review)
Single-cell RNA sequencing (RNA-seq) techniques can perform analysis of transcriptome at the single-cell level and possess an unprecedented potential for exploring signatures involved in tumor development and progression. ...
Potential of antibody-drug conjugates (ADCs) for cancer therapy
(
BioMed Central Ltd
, 2022 , Article Review)
The primary purpose of ADCs is to increase the efficacy of anticancer medications by minimizing systemic drug distribution and targeting specific cells. Antibody conjugates (ADCs) have changed the way cancer is treated. ...
Mechanical properties of human hepatic tissues to develop liver-mimicking phantoms for medical applications
(
Springer
, 2023 , Article Review)
Using liver phantoms for mimicking human tissue in clinical training, disease diagnosis, and treatment planning is a common practice. The fabrication material of the liver phantom should exhibit mechanical properties similar ...