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Obesity-induced changes in kidney mitochondria and endoplasmic reticulum in the presence or absence of leptin
(
American Physiological Society
, 2015 , Article)
We investigated obesity-induced changes in kidney lipid accumulation, mitochondrial function, and endoplasmic reticulum (ER) stress in the absence of hypertension, and the potential role of leptin in modulating these ...
A program for obese youth at-risk for diabetes in Qatar
(
Hamad bin Khalifa University Press (HBKU Press)
, 2015 , Article)
Background: Obesity is an international public health problem well documented in Qatar among children and adolescents and contributes to diabetes, a disease already highly prevalent in the country. We describe an intervention ...
Glucose- and triglyceride-lowering dietary penta-O-galloyl-α-D-glucose reduces expression of PPARγ and C/EBPα, induces p21-Mediated G1 phase cell cycle arrest, and inhibits adipogenesis in 3T3-L1 preadipocytes
(
Thieme
, 2015 , Article)
Plant polyphenols, such as hydrolysable tannins, are present in the human diet and known to exhibit anti-diabetic and anti-obesity activity. We previously reported that the representative hydrolysable tannin compound ...