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    An extensive computational approach to analyze and characterize the functional mutations in the galactose-1-phosphate uridyl transferase (GALT) protein responsible for classical galactosemia 

    S, Udhaya Kumar; D, Thirumal Kumar; R, Siva; C, George Priya Doss; Zayed, Hatem ( Elsevier , 2019 , Article)
    Type I galactosemia is a very rare autosomal recessive genetic metabolic disorder that occurs because of the mutations present in the galactose-1-phosphate uridyl transferase (GALT) gene, resulting in a deficiency of the ...
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    An integrative bioinformatics pipeline to demonstrate the alteration of the interaction between the ALDH2*2 allele with NAD and Disulfiram. 

    J, Christy Priyadharshini; D, Thirumal Kumar; P, Sneha; R, Siva; W, Charles Emmanuel Jebaraj; C, George Priya Doss; Zayed, Hatem... more authors ... less authors ( Wiley , 2019 , Article)
    Alcohol use disorder (AUD) is a multifactorial psychiatric behavior disorder. Disulfiram is the first approved drug by the Food and Drug Administration for alcohol-dependent patients, which targets the ALDH2 enzyme. Several ...
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    Enhanced production of anthraquinones by gamma-irradiated cell cultures of Rubia cordifolia in a bioreactor 

    A, Mariadoss; Satdive, Ramesh; Fulzele, Devanand P.; Ramamoorthy, Siva; C, George Priya Doss; Zayed, Hatem; Younes, Salma; C, Rajasekaran... more authors ... less authors ( Elsevier , 2019 , Article)
    The aim of this study was to obtain high-yielding cell cultures of Rubia cordifolia by applying gamma irradiation and subsequently scaling up for anthraquinone production in a bioreactor. Calli cultured on MS medium was ...

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    • C, George Priya Doss (2)
    • Zayed, Hatem (2)
    • A, Mariadoss (1) C, George Priya Doss (1) ... View More
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      ALDH2 (1) ALDH2*2 (1) Anthraquinones (1) Bioreactor (1) ... View More
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