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Resveratrol-mediated regulation of mitochondria biogenesis-associated pathways in neurodegenerative diseases: molecular insights and potential therapeutic applications.
(
Bentham Science Publisher
, 2022 , Article Review)
Neurodegenerative disorders include neurological conditions that affect nerve cells, causing the progressive loss of their functions and ultimately leading to loss of mobility, coordination, and mental functioning. The ...
The effect of nuts consumption on circulating oxidized low-density lipoproteins: A systematic review and meta-analysis of randomized controlled trials.
(
Wiley
, 2023 , Article Review)
This systematic review and meta-analysis evaluated the effect of nuts in decreasing circulating levels of oxidized low-density lipoproteins (ox-LDL). A literature search was performed of major electronic databases ...
Early metabolic impairment as a contributor to neurodegenerative disease: Mechanisms and potential pharmacological intervention
(
Wiley
, 2022 , Article Review)
The metabolic syndrome comprises a family of clinical and laboratory findings, including insulin resistance, hyperglycemia, hypertriglyceridemia, low high-density lipoprotein cholesterol levels, and hypertension, in addition ...
Therapeutic effects of statins on osteoarthritis: A review
(
Wiley
, 2022 , Article Review)
Osteoarthritis (OA) is a progressive joint disease. The etiology of OA is considered to be multifactorial. Currently, there is no definitive treatment for OA, and the existing treatments are not very effective. ...
Estrogen and Bisphenol A in Hypertension
(
Springer
, 2020 , Article Review)
Purpose of Review: Cardiovascular disease (CVD) is a non-subsiding disease that remains a leading cause of morbidity and mortality. CVD has been associated with endocrine disruptors, such as bisphenol A (BPA). This review ...
Inflammation and hypertension: Underlying mechanisms and emerging understandings
(
wiley online library
, 2023 , Article Review)
Hypertension remains a major contributor to cardiovascular disease (CVD), a leading cause of global death. One of the major insults that drive increased blood pressure is inflammation. While it is the body's defensive ...
Western diet aggravates neuronal insult in post-traumatic brain injury: Proposed pathways for interplay
(
Elsevier
, 2020 , Article Review)
Traumatic brain injury (TBI) is a global health burden and a major cause of disability and mortality. An early cascade of physical and structural damaging events starts immediately post-TBI. This primary injury event ...
The hypertensive potential of estrogen: An untold story
(
Elsevier
, 2020 , Article Review)
Cardiovascular disease (CVD) is the major cause of morbidity and mortality worldwide. The implication of estrogen in this disease has been extensively studied. While the vast majority of published research argue for a ...
The pleiotropic effects of antithrombotic drugs in the metabolic-cardiovascular-neurodegenerative disease continuum: Impact beyond reduced clotting
(
Portland Press Ltd
, 2021 , Article Review)
Antithrombotic drugs are widely used for primary and secondary prevention, as well as treatment of many cardiovascular disorders. Over the past few decades, major advances in the pharmacology of these agents have been made ...
Flavonoids in adipose tissue inflammation and atherosclerosis: One arrow, two targets
(
Portland Press Ltd
, 2020 , Article Review)
Flavonoids are polyphenolic compounds naturally occurring in fruits and vegetables, in addition to beverages such as tea and coffee. Flavonoids are emerging as potent therapeutic agents for cardiovascular as well as metabolic ...