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Chronic administration of nano-sized PAMAM dendrimers in vivo inhibits EGFR-ERK1/2-ROCK signaling pathway and attenuates diabetes-induced vascular remodeling and dysfunction.
(
Elsevier
, 2019 , Article)
We investigated whether chronic administration of nano-sized polyamidoamine (PAMAM) dendrimers can have beneficial effects on diabetes-induced vascular dysfunction by inhibiting the epidermal growth factor receptor ...
The role of protein tyrosine phosphatase (PTP)-1B in cardiovascular disease and its interplay with insulin resistance
(
MDPI AG
, 2019 , Article Review)
Endothelial dysfunction is a key feature of cardiovascular disorders associated with obesity and diabetes. Several studies identified protein tyrosine phosphatase (PTP)-1B, a member of the PTP superfamily, as a major ...
Body Shape Index Is a Stronger Predictor of Diabetes.
(
MDPI
, 2019 , Article)
Anthropometric indicators can predict the development of diabetes among adults. Among them, a new indicator (Body Shape Index) was developed. Several cohort observational studies have demonstrated that A Body Shape Index ...
Factors associated with meeting current recommendation for physical activity in scottish adults with diabetes
(
MDPI AG
, 2019 , Article)
It remains unclear which factors are instrumental in meeting the recommended physical activity in people with diabetes. We, therefore, aimed to determine the sociodemographic, health-related behavior and clinical factors ...
Impact of physical exercise on gut microbiome, inflammation, and the pathobiology of metabolic disorders
(
Society for Biomedical Diabetes Research
, 2019 , Article)
BACKGROUND: The gastrointestinal tract (GIT) harbors a complex and diverse microbial composition that outnumbers our own body cells and their gene contents. These microbes play a significant role in host metabolism and ...
Clinical pharmacy considerations in special population: Pregnancy and lactation
(
Elsevier
, 2019 , Book chapter)
The physiological changes that occur during pregnancy and lactation may affect pharmacokinetics and pharmacodynamics of drugs. Hence, administration of medications during pregnancy and lactation may require adjustments in ...
Postprandial insulin and triglyceride concentrations are suppressed in response to breaking up prolonged sitting in Qatari females
(
Frontiers Media S.A.
, 2019 , Article)
Background: Cultural, environmental and logistical factors challenge the Qatari population, particularly females, to engage in physical activity, and there is a high prevalence of diabetes in this population. Sedentary ...