Search
Now showing items 1-10 of 11
Contribution of Heparan Sulphate Binding in CCL21-Mediated Migration of Breast Cancer Cells
(
MDPI
, 2022 , Article)
Chemokine receptor CCR7 is implicated in the metastasis of breast cancer to the lymph
nodes. Chemokine function is dependent upon their binding to both cell-surface heparan sulphate
(HS) and to their specific receptors; ...
Incidence of HPVs, EBV and MMTV-like Virus in Breast Cancer in Qatar.
(
Karger Publishers
, 2022 , Article)
Human papillomaviruses (HPVs), Epstein-Barr virus (EBV), and mouse mammary tumor virus-like virus (MMTV-like virus) can be present and contribute to breast cancer development and progression. However, the role of these ...
Association of Serum 25-Hydroxyvitamin D Concentration with Breast Cancer Risk in Postmenopausal Women in the US
(
MDPI
, 2022 , Article)
The association between serum 25-hydroxyvitamin D [25(OH)D] concentration and breast
cancer risk in postmenopausal women is not well understood. The aim of this study was to investigate
the association between serum ...
Origanum syriacum L. Attenuates the Malignant Phenotype of MDA-MB231 Breast Cancer Cells
(
Frontiers Media
, 2022 , Article)
Breast cancer is the leading cause of cancer-related deaths among women. Among breast cancer types, triple negative breast cancer (TNBC) is the most aggressive, and is resistant to hormonal and chemotherapeutic treatments. ...
Human Papillomaviruses-Related Cancers: An Update on the Presence and Prevention Strategies in the Middle East and North African Regions.
(
MDPI
, 2022 , Article Review)
The human papillomavirus (HPV) is a non-enveloped double-stranded DNA virus capable of infecting skin and mucosa epithelial cells. Commonly, HPV infection is associated with sexually transmitted diseases and is considered ...
Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor.
(
Frontiers Media
, 2022 , Article)
Immune checkpoint blockade (ICB)-based therapy is revolutionizing cancer treatment by fostering successful immune surveillance and effector cell responses against various types of cancers. However, patients with HER2+ ...
SIRT1, a novel transcriptional downstream target of CD44, linking its deacetylase activity to tumor cell invasion/metastasis
(
Frontiers Media S.A.
, 2022 , Short Survey)
Our tetracycline-off-inducible CD44 expression system previously established in mouse model, revealed that activation of CD44 with its major ligand hyaluronan (HA) promoted breast cancer (BC) metastasis to the liver. To ...
PCF11, a Novel CD44-Downstream Transcriptional Target, Linking Its 3'-End Polyadenylation Function to Tumor Cell Metastasis
(
Frontiers Media S.A.
, 2022 , Article Review)
Breast Cancer (BC) is the most common and the major health issue in women worldwide. Metastasis, a multistep process, is the worst aspect of cancer and tumor cell invasion is the defining step. Tumor cell invasion requires ...
Does the Sex of the Firstborn Child Affect the Breast Cancer Risk and Survival: A Systematic Review and Meta-analysis of Over 1 Million Cases
(
Galenos Yayinevi
, 2022 , Article)
Background: Reports on the risk and prognosis of breast cancer in relation to the sex of a child have been conflicting. Since medical sciences play an important role in informing sociocultural understandings of health and ...
Carnosol Induces p38-Mediated ER Stress Response and Autophagy in Human Breast Cancer Cells
(
Frontiers
, 2022 , Article)
We recently reported that carnosol induces ROS-dependent autophagy and apoptosis in breast cancer cells. We also reported that carnosol inhibits breast cancer cell migration, invasion, and in ovo tumor growth, as well as ...