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PCF11, a Novel CD44-Downstream Transcriptional Target, Linking Its 3'-End Polyadenylation Function to Tumor Cell Metastasis
(
Frontiers Media S.A.
, 2022 , Article Review)
Breast Cancer (BC) is the most common and the major health issue in women worldwide. Metastasis, a multistep process, is the worst aspect of cancer and tumor cell invasion is the defining step. Tumor cell invasion requires ...
The Role of CCL21/CCR7 Chemokine Axis in Breast Cancer Progression
(
MDPI
, 2015 , Article Review)
Tumor-induced lymphangiogenesis facilitates breast cancer progression by generating new lymphatic vessels that serve as conduits for tumor dissemination to lymph nodes and beyond. Given the recent evidence suggesting the ...
Human Papillomaviruses-Related Cancers: An Update on the Presence and Prevention Strategies in the Middle East and North African Regions.
(
MDPI
, 2022 , Article Review)
The human papillomavirus (HPV) is a non-enveloped double-stranded DNA virus capable of infecting skin and mucosa epithelial cells. Commonly, HPV infection is associated with sexually transmitted diseases and is considered ...
Emerging roles of activating transcription factor 2 in the development of breast cancer: a comprehensive review.
(
Oxford University Press
, 2023 , Article Review)
Activating transcription factor 2 (ATF2) is a member of the leucine zipper family of DNA binding proteins that are responsible for regulating various genes that play an essential role in major biological and cellular ...
Dietary Patterns Associated with Breast Cancer in the Middle East: A Scoping Review
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2024 , Article Review)
Breast cancer (BC) is the most predominant malignancy in Arab women in the Middle East, and yearly increases in occurrence by 37.5 and mortality rates by 15.2 for every 100,000 in 2019. This review explores the gap in ...
KYNU, a novel potential target that underpins CD44-promoted breast tumour cell invasion
(
Blackwell Publishing Inc.
, 2021 , Article Review)
Using a validated tetracycline-off-inducible CD44 expression system in mouse model, we have previously demonstrated that the hyaluronan (HA) receptor CD44 promotes breast cancer (BC) metastasis to the liver. To unravel the ...
A review of breast cancer pathology reports in Nigeria
(
ecancer Global Foundation
, 2021 , Article Review)
Background: Diagnosis and treatment of cancer rely heavily on imaging, histopathology and molecular information. Incomplete or missing tumour information can hinder the delivery of high-quality care in oncology practice, ...
Glycogen-rich Clear Cell Carcinoma of the Breast: A Comprehensive Review.
(
Lippincott, Williams & Wilkins
, 2020 , Article Review)
Glycogen-rich clear cell carcinoma (GRCC) is a very rare form of primary breast cancer (<0.1% of all breast cancers). It is characterized by the presence of neoplastic cells with a glycogen-abundant clear cytoplasm (the ...
Targeted immunotherapy with a checkpoint inhibitor in combination with chemotherapy: A new clinical paradigm in the treatment of triple-negative breast cancer.
(
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
, 2019 , Article Review)
The treatment of several solid and hematologic malignancies with immune checkpoint inhibitors (against PD-1/PD-L1) has dramatically changed the cancer treatment paradigm. However, no checkpoint inhibitors were previously ...