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The impact of genetic and non-genetic factors on warfarin dose prediction in MENA region: A systematic review
(
Public Library of Science
, 2016 , Article Review)
Background Warfarin is the most commonly used oral anticoagulant for the treatment and prevention of thromboembolic disorders. Pharmacogenomics studies have shown that variants in CYP2C9 and VKORC1 genes are strongly and ...
Synthesis and cytotoxic activity of MOM-ether analogs of isosteviol
(
Elsevier Ltd.
, 2014 , Article)
Lung cancer is one of the most common malignancies worldwide. In this Letter, novel MOM-ether analogs of isosteviol were designed and synthesized to be tested for anticancer activities against H1299 lung cancer cell lines. ...
Using spectral imaging for the analysis of abnormalities for colorectal cancer: When is it helpful?
(
Public Library of Science
, 2018 , Article)
© 2018 Awan et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Impact of GGCX, STX1B and FPGS Polymorphisms on Warfarin Dose Requirements in European-Americans and Egyptians
(
Blackwell Publishing Ltd
, 2016 , Article)
Genotype-based algorithms that include VKORC1 and CYP2C9 genotypes are less predictive of warfarin dose variability in Africans as opposed to Europeans. Polymorphisms in GGCX, FPGS, or STX1B are associated with warfarin ...
Tobacco Use and Its Health Effects among Professional Athletes in Qatar
(
Hindawi Limited
, 2016 , Article)
The objective of the study was to determine the effects of tobacco use on selected markers of health and lung function in professional
athletes. A total of 108 male professional athletes participated in the study from ten ...
Evaluation of pharmacist-based compared to doctor-based anticoagulation management in Qatar
(
Blackwell Publishing Ltd
, 2016 , Article)
Rationale, aims and objectives For over 60 years, warfarin has been the mainstay anticoagulant used in the outpatient setting for the prevention and treatment of a wide variety of thromboembolic clinical conditions. ...
Metronidazole in conjunction with penicillin neither prevents recurrence nor enhances recovery from peritonsillar abscess when compared with penicillin alone: A prospective, double-blind, randomized, placebo-controlled trial
(
Oxford University Press
, 2016 , Article)
Objectives
The objectives of this study were to evaluate the efficacy of metronidazole in conjunction with penicillin in preventing the recurrence of peritonsillar abscess (PTA) and to learn whether metronidazole enhances ...
Targeting dopaminergic system for treating nicotine dependence
(
Bentham Science Publishers B.V.
, 2016 , Article)
Background: Smoking is the world's leading cause of preventable death among populations. Cigarette smoking increases the risk of numerous health problems, including heart diseases, stroke, atherosclerosis and many types ...
Towards understanding the genetics of Autism
(
Frontiers in Bioscience
, 2016 , Article Review)
Autism spectrum disorder (ASD) includes a group of neurodevelopmental disorders that affect communication skills, social interaction and intellectual ability. Despite evidence suggesting a strong genetic link with ASD, the ...
Thalamic visual prosthesis
(
IEEE Computer Society
, 2016 , Article)
Glaucoma is a neurological disorder leading to blindness initially through the loss of retinal ganglion cells, followed by loss of neurons higher in the visual system. Some work has been undertaken to develop prostheses ...