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Enzyme?polymeric/inorganic metal oxide/hybrid nanoparticle bio-conjugates in the development of therapeutic and biosensing platforms
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Elsevier B.V.
, 2021 , Article)
Background: Because enzymes can control several metabolic pathways and regulate the production of free radicals, their simultaneous use with nanoplatforms showing protective and combinational properties is of great interest ...
Structural and magnetic properties of Ni1-xZnxFe 2O4 (x=0, 0.5 and 1) nanopowders prepared by sol-gel method
(2013 , Article)
A series of nanostructured Ni-Zn ferrites Ni1-xZn xFe2O4 (x=0, 0.5 and 1) with a grain size from 24 to 65 nm have been prepared with a sol-gel method. The effect of composition and sintering temperature on morphology, ...
Plasmonic and chiroplasmonic nanobiosensors based on gold nanoparticles
(
Elsevier B.V.
, 2020 , Article)
Development of optical nanobiosensors has emerged as one of the most important bioresearch areas of interest over the past decades especially in the modern innovations in the design and utilization of sensing platforms. ...
Silybin as a potent inhibitor of a-synuclein aggregation and associated cytotoxicity against neuroblastoma cells induced by zinc oxide nanoparticles
(
Elsevier B.V.
, 2020 , Article)
a-synuclein (a-syn) amyloid fibrils, the leading neurotoxic types, are predominately formed through interaction with nanoparticles (NPs). However, some natural compounds like silybin can reduce the formation of NPs-induced ...
Sulfated alginate/polycaprolactone double-emulsion nanoparticles for enhanced delivery of heparin-binding growth factors in wound healing applications
(
Elsevier B.V.
, 2021 , Article)
Diabetic foot ulcers (DFUs) that are not effectively treated could lead to partial or complete lower limb amputations. The lack of connective tissue growth factor (CTGF) and insulin-like growth factor (IGF-I) in DFUs results ...
Nanozyme-based sensing platforms for detection of toxic mercury ions: An alternative approach to conventional methods
(
Elsevier B.V.
, 2020 , Article)
Mercury (Hg) is known as a poisonous heavy metal which stimulates a wide range of adverse effects on the human health. Therefore, development of some feasible, practical and highly sensitive platforms would be desirable ...
Exploring the interaction of synthesized nickel oxide nanoparticles through hydrothermal method with hemoglobin and lymphocytes: Bio-thermodynamic and cellular studies
(
Elsevier B.V.
, 2020 , Article)
The NiO NPs were synthesized by hydrothermal method and their interaction with Hb was investigated by employing fluorescence, UV?vis absorption techniques as well as docking studies. Also, the cytotoxic impacts of NiO NPs ...
Enzyme immobilization onto the nanomaterials: Application in enzyme stability and prodrug-activated cancer therapy
(
Elsevier B.V.
, 2020 , Article)
Nanoparticles (NPs) have been widely used for immobilization of wide ranges of enzymes. However, the stabilization of enzymes on NPs is a major challenge, crucial for regulating enzymatic activity and their medical ...
Modulation of proteomic and inflammatory signals by Bradykinin in podocytes
(
Elsevier B.V.
, 2020 , Article)
Podocyte damage is one of the hallmarks of diabetic nephropathy leading to proteinuria and kidney damage. The underlying mechanisms of podocyte injury are not well defined. Bradykinin (BK) was shown to contribute to diabetic ...
3D bioprinting of engineered breast cancer constructs for personalized and targeted cancer therapy
(
Elsevier B.V.
, 2021 , Article)
The bioprinting technique with specialized tissue production allows the study of biological, physiological, and behavioral changes of cancerous and non-cancerous tissues in response to pharmacological compounds in personalized ...