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Now showing items 591-600 of 742
Comprehensive literature review on CH4-CO2 replacement in microscale porous media
(
Elsevier B.V.
, 2018 , Article Review)
Gas production studies from natural gas hydrate reservoirs have been the subject of extensive research in recent years. Although CH4-CO2 replacement production method from gas hydrates has many advantages, the number of ...
Reuse of Sludge as Organic Soil Amendment: Insights into the Current Situation and Potential Challenges
(
MDPI
, 2023 , Article Review)
Sludge generation as an organic by-product of wastewater treatment has seen a consistent increase worldwide due to population growth and industrial activities. This poses a chronic challenge regarding management options ...
The Optimal Configuration of Wave Energy Conversions Respective to the Nearshore Wave Energy Potential
(
MDPI
, 2022 , Article Review)
Ocean energy is one potential renewable energy alternative to fossil fuels that has a more significant power generation due to its better predictability and availability. In order to harness this source, wave energy ...
Cancer immunotherapy with immune checkpoint inhibitors (ICIs): potential, mechanisms of resistance, and strategies for reinvigorating T cell responsiveness when resistance is acquired
(
BioMed Central Ltd
, 2023 , Article Review)
Cancer is still the leading cause of death globally. The approval of the therapeutic use of monoclonal antibodies against immune checkpoint molecules, notably those that target the proteins PD-1 and PD-L1, has changed the ...
Single-Cell RNA Sequencing with Spatial Transcriptomics of Cancer Tissues
(
MDPI
, 2022 , Article Review)
Single-cell RNA sequencing (RNA-seq) techniques can perform analysis of transcriptome at the single-cell level and possess an unprecedented potential for exploring signatures involved in tumor development and progression. ...
Potential of antibody-drug conjugates (ADCs) for cancer therapy
(
BioMed Central Ltd
, 2022 , Article Review)
The primary purpose of ADCs is to increase the efficacy of anticancer medications by minimizing systemic drug distribution and targeting specific cells. Antibody conjugates (ADCs) have changed the way cancer is treated. ...
Experimental Assessment of Cardiovascular Physiology in the Chick Embryo.
(
American Association for Anatomy Journals
, 2023 , Article Review)
High resolution assessment of cardiac functional parameters is crucial in translational animal research. The chick embryo is a historically well-used in vivo model for cardiovascular research due to its many practical ...
Selective Activation of G protein-coupled Estrogen Receptor 1 Attenuates Atherosclerosis.
(
Bentham Science Publishers
, 2023 , Article Review)
Atherosclerosis remains a leading contributor to cardiovascular disease-associated morbidity and mortality. Interestingly, the death rate is higher in men than women from atherosclerosis, and the risk increases for ...
Western diet aggravates neuronal insult in post-traumatic brain injury: Proposed pathways for interplay
(
Elsevier
, 2020 , Article Review)
Traumatic brain injury (TBI) is a global health burden and a major cause of disability and mortality. An early cascade of physical and structural damaging events starts immediately post-TBI. This primary injury event ...
Recent developments on (−)-colchicine derivatives: Synthesis and structure-activity relationship
(
Elsevier
, 2020 , Article Review)
(−)-Colchicine, an anti-microtubulin polymerization agent, is a valuable medication and the drug of choice for gout, Behçet’s disease and familial Mediterranean fever. It has a narrow therapeutic index due to its high ...