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Antimicrobial Resistance Profiles for Different Isolates in Aden, Yemen: A Cross-Sectional Study in a Resource-Poor Setting
(
Hindawi Limited
, 2020 , Article)
Background. There is a rapid deterioration in the effectiveness of antibiotics due to the global prevalence of bacterial antimicrobial resistance (AMR). AMR can cause an increase in mortality and morbidity due to treatment ...
Core outcomes in gestational diabetes for treatment trials: The Gestational Metabolic Group treatment set
(
John Wiley and Sons Inc
, 2021 , Article)
Aims
With the rising number of outcomes being reported following gestational diabetes (GDM), the outcomes in existing studies vary widely making it challenging to compare and contrast the effectiveness of different ...
Towards a better understanding of self-management interventions in type 2 diabetes: A concept analysis
(
Elsevier Ltd
, 2022 , Article)
Objectives: Diabetes self-management educational (DSME) interventions can vary considerably, and it is unclear what is the operational conceptualization of the ideal delivery to individuals with type 2 diabetes (T2D). ...
Mortality prediction utilizing blood biomarkers to predict the severity of COVID-19 using machine learning technique
(
MDPI
, 2021 , Article)
Healthcare researchers have been working on mortality prediction for COVID-19 patients with differing levels of severity. A rapid and reliable clinical evaluation of disease intensity will assist in the allocation and ...
Generation of gene edited hiPSC from familial Alzheimer's disease patient carrying N141I missense mutation in presenilin 2
(
Elsevier B.V.
, 2021 , Article)
Alzheimer's disease (AD) is the major cause of dementia worldwide. Early-onset familial AD accounts for about 0.5% of all AD and is caused by single major gene mutations and autosomal dominant inheritance. An N141I missense ...
Biomimetic trace metals improve bone regenerative properties of calcium phosphate bioceramics
(
John Wiley and Sons Inc
, 2021 , Article)
The bone regenerative capacity of synthetic calcium phosphates (CaPs) can be enhanced through the enrichment with selected metal trace ions. However, defining the optimal elemental composition required for bone formation ...
The effect of aging on the bone healing properties of blood plasma
(
Elsevier Ltd
, 2021 , Article)
Objectives: Age-related changes in blood composition have been found to affect overall health. Thus, this study aimed to understand the effect of these changes on bone healing by assessing how plasma derived from young and ...
Multiscale structural evolution of citrate-triggered intrafibrillar and interfibrillar mineralization in dense collagen gels
(
Academic Press Inc.
, 2020 , Article)
The mineralized extracellular matrix of bone is an organic?inorganic nanocomposite consisting primarily of carbonated hydroxyapatite, fibrous type I collagen, noncollagenous proteins, proteoglycans, and diverse biomolecules ...
Nanotoxicology of dendrimers in the mammalian heart: Ex vivo and in vivo administration of g6 pamam nanoparticles impairs recovery of cardiac function following ischemia-reperfusion injury
(
Dove Medical Press Ltd.
, 2020 , Article)
Aim: The effects of polyamidoamine (PAMAM) dendrimers on the mammalian heart are not completely understood. In this study, we have investigated the effects of a sixth-generation cationic dendrimer (G6 PAMAM) on cardiac ...
Ranitidine Impairs Bone Healing and Implant Osseointegration in Rats' Tibiae
(
W.B. Saunders
, 2020 , Article)
Purpose: Ranitidine has been found to have an impact on bone metabolism by suppressing osteoclastogenesis. We hypothesized that the use of ranitidine would impair bone healing and implant osseointegration. This study ...