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AMP-activated protein kinase as a drug target in chronic kidney disease
( Bentham Science Publishers B.V. , 2018 , Article Review)
Background: Chronic kidney disease (CKD) is a condition increasingly affecting millions of individuals worldwide and is ranked as the ninth leading cause of death in the United States. AMP-activated protein kinase (AMPK) ...
Cisplatin based therapy: The role of the mitogen activated protein kinase signaling pathway
( BioMed Central Ltd. , 2018 , Article Review)
Cisplatin is a widely used chemotherapeutic agent for treatment of various cancers. However, treatment with cisplatin is associated with drug resistance and several adverse side effects such as nephrotoxicity, reduced ...