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Influence of the Aryl Hydrocarbon Receptor Activating Environmental Pollutants on Autism Spectrum Disorder
(
MDPI
, 2021 , Article Review)
Autism spectrum disorder (ASD) is an umbrella term that includes many different disorders that affect the development, communication, and behavior of an individual. Prevalence of ASD has risen exponentially in the past ...
Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patients
(
Frontiers Media S.A.
, 2023 , Article)
Immune checkpoint inhibitors (ICIs) including anti-PD-1 and anti-PD-L1 antibodies, have significantly changed the treatment outcomes of NSCLC patients with better overall survival. However, 15-40% of the patients still ...
Sestrin2 as a Protective Shield against Cardiovascular Disease
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
A timely and adequate response to stress is inherently present in each cell and is important for maintaining the proper functioning of the cell in changing intracellular and extracellular environments. Disruptions in the ...
Letter to the Editor Response
(
Elsevier
, 2020 , Other)
To the Editor
We thank Dr. Luis Rafael Moscote-Salazar and Dr. Amit Agrawal for their interest in our recently published article in the Journal.1 The authors do not raise any concerns about the scientific facts and the ...
Molecular Mechanisms Underpinning Microparticle-Mediated Cellular Injury in Cardiovascular Complications Associated with Diabetes.
(
Hindawi
, 2019 , Article)
Microparticles (MPs) are small vesicles shed from the cytoplasmic membrane of healthy, activated, or apoptotic cells. MPs are very heterogeneous in size (100-1,000 nm), and they harbor proteins and surface antigens specific ...
Corneal nerve loss in patients with TIA and acute ischemic stroke in relation to circulating markers of inflammation and vascular integrity
(
Nature Research
, 2022 , Article)
Vascular and inflammatory mechanisms are implicated in the development of cerebrovascular disease and corneal nerve loss occurs in patients with transient ischemic attack (TIA) and acute ischemic stroke (AIS). We have ...
Complement C5a and Clinical Markers as Predictors of COVID-19 Disease Severity and Mortality in a Multi-Ethnic Population
(
Frontiers Media S.A.
, 2021 , Article)
Coronavirus disease-2019 (COVID-19) was declared as a pandemic by WHO in March 2020. SARS-CoV-2 causes a wide range of illness from asymptomatic to life-threatening. There is an essential need to identify biomarkers to ...
Human antigen R: Exploring its inflammatory response impact and significance in cardiometabolic disorders
(
Wiley
, 2024 , Article Review)
RNA-binding proteins (RBPs) play a crucial role in the regulation of posttranscriptional RNA networks, which can undergo dysregulation in many pathological conditions. Human antigen R (HuR) is a highly researched RBP that ...
Differentially expressed miRNA profiles of serum derived extracellular vesicles from patients with acute ischemic stroke
(
Elsevier
, 2024 , Report)
BackgroundMicroRNAs (miRNAs) participate in diverse cellular changes following acute ischemic stroke (AIS). Circulating miRNAs, stabilized and delivered to target cells via extracellular vesicles (EVs), are potential ...