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Interleukin-2: Evaluation of routes of administration and current delivery systems in cancer therapy
(
Wiley Subscription Services, Inc., A Wiley Company
, 2009 , Article)
Despite the fact that different administration routes and delivery systems have been used for interleukin-2 (IL-2) delivery, little has been reported regarding the most efficient strategies used to deliver IL-2 in a nontoxic, ...
Pharmacoeconomics of voriconazole in the management of invasive fungal infections
(
Taylor and Francis
, 2010 , Article)
The incidence of invasive fungal infection has risen in recent years with the introduction of more intensive chemotherapy regimens and the advent of stem cell and solid-organ transplants. In patients undergoing chemotherapy, ...
Incidence, severity and preventability of medication-related visits to the emergency department: A prospective study
(
Canadian Medical Association
, 2008 , Article)
Background: Medication-related visits to the emergency department are an important but poorly understood phenomenon. We sought to evaluate the frequency, severity and preventability of drug-related visits to the emergency ...
Structure–activity relationship of piperine and its synthetic amide analogs for therapeutic potential to prevent experimentally induced ER stress in vitro
(
Springer Netherlands
, 2017 , Article)
Endoplasmic reticulum (ER) is the key organelle involved in protein folding and maturation. Emerging studies implicate the role of ER stress in the development of chronic kidney disease. Thus, there is an urgent need for ...
Microbial production of 1α-hydroxyvitamin D3 from vitamin D3
(
Taylor and Francis Ltd.
, 2014 , Article)
The microbial transformation of vitamin D3 (1) by the fungi Candida maltosa R42 and Botrytis allii NRRL 2502 was investigated. Incubation of compound 1 with C. maltosa R42 and B. allii NRRL 2502 produced the same three ...
Pharmacokinetics of ertapenem in critically ill patients receiving continuous venovenous hemodialysis or hemodiafiltration
(
American Society for Microbiology
, 2014 , Article)
This study characterizes the pharmacokinetics of ertapenem, a carbapenem antibiotic, in critically ill adult subjects receiving continuous renal replacement therapy (CRRT). Eight critically ill patients with suspected/known ...
Evaluation of the Anti-melanoma Activities of Sarcophine, (+)-7α,8β-Dihydroxydeepoxysarcophine and Sarcophytolide from the Red Sea Soft Coral Sarcophyton glaucum
(
Natural Product Communications, Inc.
, 2014 , Article)
Abstract - Three natural cembranoids from the Red Sea soft coral Sarcophyton glaucum
namely sarcophine (1), (+)-7α,8β-dihydroxydeepoxysarcophine (2) and sarcophytolide
(3) were evaluated for their potential inhibitory ...
Cost-benefit analysis of clinical pharmacist intervention in preventing adverse drug events in the general chronic diseases outpatients.
(
Wiley
, 2019 , Article)
Clinical pharmacy services are vital in the prevention of adverse drug events (ADEs) in clinical practice, extending beyond the hospital to chronic disease management in outpatient settings. This study sought to evaluate ...
Evaluation of anti-melanoma activities of (1S,2E,4R,6E,8R,11S,12R)-8,12- epoxy-2,6-cembradiene-4,11-diol, (1S,2E,4R,6E,8S,11R,12S)-8,11-epoxy-4,12-epoxy- 2,6-cembradiene and (1S,4R,13S)-cembra-2E,7E,11E-trien-4,13-diol from the Red Sea soft coral Sarcophyton glaucum
(
Natural Product Communications
, 2014 , Article)
Three natural cembranoids from the Red Sea soft coral Sarcophyton glaucum namely (1S,2E,4R,6E,8R,11S,12R)-8,12-epoxy-2,6-cembradiene-4,11-diol, (1S,2E,4R,6E,8S,11R,12S)-8,11-epoxy-4,12-epoxy-2,6-cembradiene and ...
Nephroprotective Effects of Metformin in Diabetic Nephropathy
(
Wiley
, 2017 , Article)
Metformin, a well-known anti-diabetic agent, is very effective in lowering blood glucose in patients with type 2 diabetes with minimal side-effects. Metformin is also being recommended in the treatment of obesity and ...