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Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region
(
Springer International Publishing
, 2017 , Article Review)
Background
Genetic polymorphisms are known to influence outcomes with phenytoin yet effects in the Middle East and North Africa region are poorly understood.
Objectives
The objective of this systematic review was to ...
The role of mid-chain hydroxyeicosatetraenoic acids in the pathogenesis of hypertension and cardiac hypertrophy
(
Springer Verlag
, 2016 , Article Review)
The incidence, prevalence, and hospitalization rates associated with cardiovascular diseases (CVDs) are projected to increase substantially in the world. Understanding of the biological and pathophysiological mechanisms ...
A systematic review of pharmaceutical pricing policies in developing countries
(
Blackwell Publishing Ltd
, 2017 , Article Review)
Objective
A systematic review was conducted to summarize government strategies aimed at controlling pharmaceutical prices in developing countries and their effects on relevant outcomes, and to qualitatively analyse eligible ...
A Systematic Scoping Review of the State of Pharmacovigilance and Governance in the MENA Region: Challenges and Opportunities
(
Springer International Publishing
, 2017 , Article Review)
Introduction
Pharmacovigilance (PV) systems around the world vary in capacity and maturity. Many factors can influence PV.
Objectives
This systematic scoping review aims to explore the opportunities for effective PV ...
Myocardial proteases and cardiac remodeling
(
Wiley-Liss Inc.
, 2017 , Article Review)
Cardiac hypertrophy (CH), characterized by the enlargement of cardiomyocytes, fibrosis and apoptosis, is one of the leading causes of death worldwide. Despite the advances in cardiovascular research, there remains a need ...
Creation of an inventory of quality markers used to evaluate pharmacokinetic literature: A systematic review
(
Wiley
, 2021 , Article Review)
What is known and objective: Robust critical appraisal tools for clinical pharmacokinetic studies are limited. Before development of such a tool is possible, quality markers (items deemed important for credibility of study ...
Macroalgal polysaccharides in biomimetic nanodelivery systems
(
Bentham Science Publishers
, 2019 , Article Review)
Background: Imitating nature in the design of bio-inspired drug delivery systems resulted in several success stories. However, the practical application of biomimicry is still largely unrealized owing to the fact that we ...
A systematic review of pharmacist input to metabolic syndrome screening, management and prevention.
(
Springer
, 2020 , Article Review)
Background Metabolic syndrome is a cluster of factors that increase the risk of cardiovascular disease and include: diabetes and prediabetes, abdominal obesity, elevated triglycerides, low high-density lipoprotein cholesterol ...
Future perspectives on nonmedical prescribing
(
SAGE Publications Ltd
, 2017 , Article Review)
Many countries have implemented nonmedical prescribing (NMP) and many others are scoping prescribing practices with a view to developing NMP. This paper provides a future perspective on NMP in light of findings of an ...
Anticancer potential of sanguinarine for various human malignancies
(
Future Medicine Ltd.
, 2017 , Article Review)
Sanguinarine (Sang) - a benzophenanthridine alkaloid extracted from Sanguinaria canadensis - exhibits antioxidant, anti-inflammatory, proapoptotic and growth inhibitory activities on tumor cells of various cancer types as ...