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Evidence-Based Review of Pharmacotherapy Used for Parkinson's Disease Psychosis
(
SAGE Publications Inc.
, 2017 , Article Review)
Objective: To summarize and evaluate the existing literature regarding medications to treat Parkinson's disease (PD) psychosis. Data Sources: MEDLINE (1946 to March 2017), EMBASE (1980 to March 2017), CINAHL (1982 to March ...
Metformin Induces Different Responses in Clear Cell Renal Cell Carcinoma Caki Cell Lines.
(
MDPI
, 2019 , Article)
Clear cell renal cell carcinoma (ccRCC) is the most common and lethal form of urological cancer diagnosed globally. Mutations of the von Hippel-Lindau tumor-suppressor gene and the resultant overexpression of hypoxia-inducible ...
Crosstalk Between Oxidative Stress and Endoplasmic Reticulum (ER) Stress in Endothelial Dysfunction and Aberrant Angiogenesis Associated With Diabetes: A Focus on the Protective Roles of Heme Oxygenase (HO)-1
(
Frontiers Media
, 2019 , Article Review)
Type-2 diabetes prevalence is continuing to rise worldwide due to physical inactivity and obesity epidemic. Diabetes and fluctuations of blood sugar are related to multiple micro- and macrovascular complications, that are ...
Blind Source Separation Algorithms Using Hyperbolic and Givens Rotations for High-Order QAM Constellations
(
Institute of Electrical and Electronics Engineers Inc.
, 2018 , Article)
This paper addresses the problem of blind demixing of instantaneous mixtures in a multiple-input multiple-output communication system. The main objective is to present efficient blind source separation (BSS) algorithms ...
Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects
(
Taylor and Francis Ltd
, 2019 , Article)
Although a plethora of studies have examined tobacco smoke-cancer disease association, the involvement of cellular genetic toxicity remains unclear. Therefore, the present study provides molecular evidence for a pathway ...
Appropriateness of Dabigatran and Rivaroxaban Prescribing in Qatar: A 5-Year Experience
(
SAGE Publications Ltd
, 2018 , Article)
Introduction: Over the past few years, direct oral anticoagulants (DOACs) have been gradually replacing warfarin. Inappropriate prescribing of DOACs in real-life practice settings can affect their perceived safety and ...
A systematic review of the outcome data supporting the Healthy Living Pharmacy concept and lessons from its implementation
(
Public Library of Science
, 2019 , Article)
Background The Healthy Living Pharmacy (HLP) project, launched in England, UK in 2009 was a novel approach of introducing public health services within community pharmacy to tackle local health inequalities. A national ...
Sanguinarine suppresses growth and induces apoptosis in childhood acute lymphoblastic leukemia
(
Taylor and Francis Ltd
, 2019 , Article)
Sanguinarine (Sang), a plant-derived compound isolated from the roots of Sanguinaria canadensis was evaluated for its potential pro-apoptotic effects in precursor B acute lymphoblastic leukemia (Pre-ALL) cell lines. Treatment ...
Tobacco-related education in schools of pharmacy in the Middle East: A multinational cross-sectional study
(
Oxford University Press
, 2018 , Article)
Background: Lack of adequate tobacco-related content in pharmacy curricula can interfere with pharmacist's ability to provide tobacco cessation interventions. This study aims to determine the extent of tobacco-related ...
Preparation and characterization of letrozole-loaded poly(d,l-lactide) nanoparticles for drug delivery in breast cancer therapy
(
Taylor and Francis Ltd
, 2019 , Article)
Letrozole (LTZ), an aromatase inhibitor used for the treatment of hormonally-positive breast cancer in postmenopausal women, has poor water solubility, rapid metabolism, and a range of side effects. In this study, polymer-based ...