Browsing Mechanical & Industrial Engineering by Author "Cenciarelli, Carlo"
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Cancer immunotherapy with immune checkpoint inhibitors (ICIs): potential, mechanisms of resistance, and strategies for reinvigorating T cell responsiveness when resistance is acquired
Marei, Hany E.; Hasan, Anwarul; Pozzoli, Giacomo; Cenciarelli, Carlo ( BioMed Central Ltd , 2023 , Article Review)Cancer is still the leading cause of death globally. The approval of the therapeutic use of monoclonal antibodies against immune checkpoint molecules, notably those that target the proteins PD-1 and PD-L1, has changed the ... -
Cholinergic and dopaminergic neuronal differentiation of human adipose tissue derived mesenchymal stem cells.
Marei, Hany El Sayed; El-Gamal, Aya; Althani, Asma; Afifi, Nahla; Abd-Elmaksoud, Ahmed; Farag, Amany; Cenciarelli, Carlo; Thomas, Caceci; Anwarul, Hasan... more authors ... less authors ( Wiley , 2018 , Article)Mesenchymal stem cells (MSCs) are multipotent cells that can differentiate into various cell types such as cartilage, bone, and fat cells. Recent studies have shown that induction of MSCs in vitro by growth factors including ... -
Glioma extracellular vesicles for precision medicine: prognostic and theragnostic application
Marei, Hany E.; Althani, Asmaa; Afifi, Nahla; Hasan, Anwarul; Caceci, Thomas; Cifola, Ingrid; Caratelli, Sara; Sconocchia, Giuseppe; D’Agnano, Igea; Cenciarelli, Carlo... more authors ... less authors ( Springer , 2022 , Article Review)EV produced by tumour cells carry a diverse population of proteins, lipids, DNA, and RNA molecules throughout the body and appear to play an important role in the overall development of the disease state, according to ... -
Potential of antibody-drug conjugates (ADCs) for cancer therapy
Marei, Hany E.; Cenciarelli, Carlo; Hasan, Anwarul ( BioMed Central Ltd , 2022 , Article Review)The primary purpose of ADCs is to increase the efficacy of anticancer medications by minimizing systemic drug distribution and targeting specific cells. Antibody conjugates (ADCs) have changed the way cancer is treated. ...