Browsing Mechanical & Industrial Engineering by Author "Hasan, Anwarul"
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3D Bioprinted cancer models: Revolutionizing personalized cancer therapy
Augustine R.; Kalva S.N.; Ahmad R.; Zahid A.A.; Hasan S.; Nayeem A.; McClements L.; Hasan, Anwarul... more authors ... less authors ( Neoplasia Press, Inc. , 2021 , Article)After cardiovascular disease, cancer is the leading cause of death worldwide with devastating health and economic consequences, particularly in developing countries. Inter-patient variations in anti-cancer drug responses ... -
Active agents loaded extracellular matrix mimetic electrospun membranes for wound healing applications
Kalva S.N.; Augustine R.; Al Mamun A.; Dalvi Y.B.; Vijay N.; Hasan, Anwarul... more authors ... less authors ( Editions de Sante , 2021 , Article)Achieving the healing of chronic diabetic ulcers, burn wounds and large traumatic wounds is a major clinical challenge. A variety of approaches have been undertaken to generate skin substitutes, wound healing patches or ... -
Bubaline Cholecyst Derived Extracellular Matrix for Reconstruction of Full Thickness Skin Wounds in Rats
Shakya, P.; Sharma, A.K.; Kumar, N.; Vellachi, R.; Mathew, D.D.; Dubey, P.; Singh, K.; Shrivastava, S.; Shrivastava, S.; Maiti S.K.; Hasan, Anwarul; Singh K.P.... more authors ... less authors ( Hindawi Limited , 2016 , Article)An acellular cholecyst derived extracellular matrix (b-CEM) of bubaline origin was prepared using anionic biological detergent. Healing potential of b-CEM was compared with commercially available collagen sheet (b-CS) and ... -
Cancer immunotherapy with immune checkpoint inhibitors (ICIs): potential, mechanisms of resistance, and strategies for reinvigorating T cell responsiveness when resistance is acquired
Marei, Hany E.; Hasan, Anwarul; Pozzoli, Giacomo; Cenciarelli, Carlo ( BioMed Central Ltd , 2023 , Article Review)Cancer is still the leading cause of death globally. The approval of the therapeutic use of monoclonal antibodies against immune checkpoint molecules, notably those that target the proteins PD-1 and PD-L1, has changed the ... -
Cerium oxide NPs mitigate the amyloid formation of α-synuclein and associated cytotoxicity
Zand Z.; Khaki P.A.; Salihi A.; Sharifi M.; Nanakali N.M.Q.; Alasady A.A.B.; Aziz F.M.; Shahpasand K.; Hasan, Anwarul; Falahati M.... more authors ... less authors ( Dove Medical Press Ltd. , 2019 , Article)Aim: Among therapeutic proposals for amyloid-associated disorders, special attention has been given to the exploitation of nanoparticles (NPs) as promising agents against aggregation. Methods: In this paper, the inhibitory ... -
Characterization and In vitro biocompatibility analysis of nanocellulose scaffold for tissue engineering application
Unni, R.; Unni, Rekha; Varghese, Ruby; Bharat Dalvi, Yogesh; Augustine, Robin; M.S, Latha; R, Reshmy; Kumar Bhaskaran Nair, Hari; Hasan, Anwarul; A, Abraham; Mathew, Tiju Joseph... more authors ... less authors ( Springer Science and Business Media B.V. , 2022 , Article)Tissue engineering aims to exploit the regenerative capacity of cells and connect the inherent ability of the body to repair and regenerate. Cells are seeded onto a porous three-dimensional scaffold in tissue engineering, ... -
Cisplatin encapsulated nanoparticles from polymer blends for anti-cancer drug delivery
Joshy, K.S.; Augustine, Robin; Hasan, Anwarul; Ali Zahid, Alap; Alex, Susan M.; Dalvi, Yogesh B.; Mraiche, Fatima; Thomas, Sabu; Kalarikkal, Nandakumar; Chi, Hong... more authors ... less authors ( Royal Society of Chemistry , 2022 , Article)Developing novel nanocarriers for anticancer drug delivery has become a ‘promising niche’. The toxicity of the carrier and its efficacy in treatment modalities have become cardinal points as they can impede the progress ... -
Empagliflozin inhibits angiotensin II-induced hypertrophy in H9c2 cardiomyoblasts through inhibition of NHE1 expression
Abdulrahman, Nabeel; Ibrahim, Meram; Joseph, Jensa Mariam; Elkoubatry, Hanan Mahmoud; Al-Shamasi, Al Anood; Rayan, Menatallah; Gadeau, Alain Pierre; Ahmed, Rashid; Eldassouki, Hussein; Hasan, Anwarul; Mraiche, Fatima... more authors ... less authors ( Springer , 2022 , Article)Diabetes mellitus (DM)-induced cardiac morbidities have been the leading cause of death among diabetic patients. Recently, sodium-glucose cotransporter-2 (SGLT-2) inhibitors including empagliflozin (EMPA), which have been ... -
Gelatin-methacryloyl hydrogel based in vitro blood–brain barrier model for studying breast cancer-associated brain metastasis
Augustine, Robin; Zahid, Alap Ali; Mraiche, Fatima; Alam, Khurshid; Al Moustafa, Ala-Eddin; Hasan, Anwarul... more authors ... less authors ( Taylor and Francis Ltd. , 2021 , Article)Breast cancer is one of the leading causes of brain metastasis. Metastasis to the brain occurs if cancer cells manage to traverse the ‘blood-brain barrier’ (BBB), which is a barrier with a very tight junction (TJ) of ... -
Halloysite nanotube and chitosan polymer composites: Physicochemical and drug delivery properties
Paul, A.; Paul, Alapan; Augustine, Robin; Hasan, Anwarul; Zahid, Alap Ali; Thomas, Sabu; Agatemor, Christian; Ghosal, Kajal... more authors ... less authors ( Editions de Sante , 2022 , Article)Advancement in healthcare requires sophisticated and safe drug delivery systems. An ideal drug delivering system should be non-toxic, therapeutically inert, and be able to deliver a wide range of drugs. Here, we report ... -
Mechanical properties of human hepatic tissues to develop liver-mimicking phantoms for medical applications
Lemine, Aicha S.; Ahmad, Zubair; Al-Thani, Noora J.; Hasan, Anwarul; Bhadra, Jolly ( Springer , 2023 , Article Review)Using liver phantoms for mimicking human tissue in clinical training, disease diagnosis, and treatment planning is a common practice. The fabrication material of the liver phantom should exhibit mechanical properties similar ... -
Nanoparticles in tissue engineering: Applications, challenges and prospects
Hasan, Anwarul; Morshed M.; Memic A.; Hassan S.; Webster T.J.; Marei H.E.-S.... more authors ... less authors ( Dove Medical Press Ltd. , 2018 , Article)Tissue engineering (TE) is an interdisciplinary field integrating engineering, material science and medical biology that aims to develop biological substitutes to repair, replace, retain, or enhance tissue and organ-level ... -
Nitric oxide-releasing biomaterials for promoting wound healing in impaired diabetic wounds: State of the art and recent trends
Ahmed, R.; Ahmed, Rashid; Augustine, Robin; Chaudhry, Maryam; Akhtar, Usman A.; Zahid, Alap Ali; Tariq, Muhammad; Falahati, Mojtaba; Ahmad, Irfan S.; Hasan, Anwarul... more authors ... less authors ( Elsevier Masson s.r.l. , 2022 , Article)Impaired diabetic wounds are serious pathophysiological complications associated with persistent microbial infections including failure in the closure of wounds, and the cause of a high frequency of lower limb amputations. ... -
Single-Cell RNA Sequencing with Spatial Transcriptomics of Cancer Tissues
Ahmed, Rashid; Zaman, Tariq; Chowdhury, Farhan; Mraiche, Fatima; Tariq, Muhammad; Ahmad, Irfan S.; Hasan, Anwarul... more authors ... less authors ( MDPI , 2022 , Article Review)Single-cell RNA sequencing (RNA-seq) techniques can perform analysis of transcriptome at the single-cell level and possess an unprecedented potential for exploring signatures involved in tumor development and progression. ...