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An engineered microfluidic blood-brain barrier model to evaluate the anti-metastatic activity of β-boswellic acid
(
John Wiley and Sons Inc
, 2021 , Article)
Background
The development of anti-cancer drugs with the ability to inhibit brain metastasis through the blood-brain barrier (BBB) is substantially limited due to the lack of reliable in vitro models.
Main Methods
In ...
Current progress in chimeric antigen receptor T cell therapy for glioblastoma multiforme
(
John Wiley and Sons Inc
, 2021 , Article)
Glioblastoma multiforme (GBM) is one of the deadliest brain tumors with an unfavorable prognosis and overall survival of approximately 20 months following diagnosis. The current treatment for GBM includes surgical resections ...