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Combined chemo-magnetic field-photothermal breast cancer therapy based on porous magnetite nanospheres
(
Nature Research
, 2020 , Article)
The efficacy of different modalities of treating breast cancer is inhibited by several limitations such as off-targeted drug distribution, rapid drug clearance, and drug resistance. To overcome these limitations, we developed ...
Loop-mediated isothermal amplification (Lamp): A rapid, sensitive, specific, and cost-effective point-of-care test for coronaviruses in the context of covid-19 pandemic
(
MDPI
, 2020 , Article)
The rampant spread of COVID-19 and the worldwide prevalence of infected cases demand a rapid, simple, and cost-effective Point of Care Test (PoCT) for the accurate diagnosis of this pandemic. The most common molecular tests ...
Exosomes: Multiple-targeted multifunctional biological nanoparticles in the diagnosis, drug delivery, and imaging of cancer cells
(2020 , Article)
Exosomes are biological nanoparticles (30−150 nm) secreted in the extracellular area from all of cells, that mediate intercellular message. Exosomes act as the carriers for numerous proteins, DNAs, RNAs and cell-signaling ...
Structure and Rheological Properties of Bovine Aortic Heart Valve and Pericardium Tissue: Implications in Bioprosthetic and Tissue-Engineered Heart Valves
(
Hindawi Limited
, 2019 , Article)
Heart valve (HV) diseases are among the leading causes of cardiac failure and deaths. Of the various HV diseases, damaged HV leaflets are among the primary culprits. In many cases, impaired HV restoration is not always ...
Stem cell-based approaches in cardiac tissue engineering: controlling the microenvironment for autologous cells
(
Elsevier
, 2021 , Article)
Cardiovascular disease is one of the leading causes of mortality worldwide. Cardiac tissue engineering strategies focusing on biomaterial scaffolds incorporating cells and growth factors are emerging as highly promising ...
Single-Cell RNA Sequencing with Spatial Transcriptomics of Cancer Tissues
(
MDPI
, 2022 , Article Review)
Single-cell RNA sequencing (RNA-seq) techniques can perform analysis of transcriptome at the single-cell level and possess an unprecedented potential for exploring signatures involved in tumor development and progression. ...
Glioma extracellular vesicles for precision medicine: prognostic and theragnostic application
(
Springer
, 2022 , Article Review)
EV produced by tumour cells carry a diverse population of proteins, lipids, DNA, and RNA molecules throughout the body and appear to play an important role in the overall development of the disease state, according to ...
Cerium oxide NPs mitigate the amyloid formation of α-synuclein and associated cytotoxicity
(
Dove Medical Press Ltd.
, 2019 , Article)
Aim: Among therapeutic proposals for amyloid-associated disorders, special attention has been given to the exploitation of nanoparticles (NPs) as promising agents against aggregation. Methods: In this paper, the inhibitory ...
Recent advances in 3D bioprinting of musculoskeletal tissues
(
IOP Publishing Ltd
, 2021 , Article)
The musculoskeletal system is essential for maintaining posture, protecting organs, facilitating locomotion, and regulating various cellular and metabolic functions. Injury to this system due to trauma or wear is common, ...
Magnetic nanocatalysts as multifunctional platforms in cancer therapy through the synthesis of anticancer drugs and facilitated Fenton reaction
(
Elsevier B.V.
, 2021 , Article)
Background: Heterocyclic compounds have always been used as a core portion in the development of anticancer drugs. However, there is a pressing need for developing inexpensive and simple alternatives to high-cost and complex ...