Mechanical & Industrial Engineering: Recent submissions
Now showing items 781-800 of 1462
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Non-viral delivery systems of DNA into stem cells: Promising and multifarious actions for regenerative medicine
( Editions de Sante , 2020 , Article)Regenerative medicine has an exciting prospective to bring preventive and therapeutic benefits to a myriad of diseases. Different biological factors such as growth factors, therapeutic proteins, antibodies, plasmid DNA ... -
Advances of exosome isolation techniques in lung cancer
( Springer Science and Business Media B.V. , 2020 , Article)Lung cancer (LC) is among the leading causes of death all over the world and it is often diagnosed at advanced or metastatic stages. Exosomes, derived from circulating vesicles that are released from the multivesicular ... -
Development of point-of-care nanobiosensors for breast cancers diagnosis
( Elsevier B.V. , 2020 , Article)Nanobiosensors have played a key role as portable devices in the rapid breast cancer diagnosis and in clinical medicine like point-of-care devices. However, understanding biomarkers and nanomaterials is crucial for improving ... -
Exploring the interaction of cobalt oxide nanoparticles with Albumin, leukemia cancer cells and pathogenic bacterial by multispectroscopic, docking, cellular and antibacterial approaches
( Dove Medical Press Ltd. , 2020 , Article)Aim: The interaction of NPs with biological systems may reveal useful details about their pharmacodynamic, anticancer and antibacterial effects. Methods: Herein, the interaction of as-synthesized Co3O4 NPs with HSA was ... -
Oxygen generating polymeric nano fibers that stimulate angiogenesis and show efficient wound healing in a diabetic wound model
( Dove Medical Press Ltd. , 2020 , Article)Introduction: Diabetic wounds are challenging to treat due to a wide range of pathophysiological changes. Hypoxia is one of the predominant contributing factors of poor vascularization and chronicity in diabetic wounds. ... -
The expression level of angiotensin-converting enzyme 2 determines the severity of COVID-19: lung and heart tissue as targets
( Taylor and Francis Ltd. , 2020 , Article)Researchers have reported some useful information about the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leading to CoV disease 2019 (COVID-19). Several studies have been performed in order to develop ... -
Development of remdesivir repositioning as a nucleotide analog against COVID-19 RNA dependent RNA polymerase
( Taylor and Francis Ltd. , 2020 , Article)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative representative of a severe respiratory illness resulted in widespread human infections and deaths in nearly all of the countries since late 2019. ... -
Experimental study on the mechanical properties of biological hydrogels of different concentrations
( IOS Press BV , 2020 , Article)BACKGROUND: Biological hydrogels provide a conducive three-dimensional extracellular matrix environment for encapsulating and cultivating living cells. Microenvironmental modulus of hydrogels dictates several characteristics ... -
Antioxidant properties of gold nanozyme: A review
( Elsevier B.V. , 2020 , Article)AuNPs with enzyme-like features have received strong attention in different areas, although limited data is available in literature on their biological/industrial functions. NPs especially Au counterparts have been shown ... -
Cellular response to nanobiomaterials
( Elsevier , 2020 , Book chapter)The application of nanobiomaterials in biomedical field is rapidly processing, especially in the areas where conventional approaches have limited success. Cell fate is mainly influenced by interactions between cells and ... -
Multimodal applications of phytonanoparticles
( Elsevier , 2020 , Book chapter)The emergence of nanotechnology has revolutionized modern life due to its diverse applications in healthcare, agriculture, the environment, and other technological applications. Growing concerns over the toxicity of ... -
Osteopontin: A Promising Therapeutic Target in Cardiac Fibrosis
( NLM (Medline) , 2019 , Article)Osteopontin (OPN) is recognized for its significant roles in both physiological and pathological processes. Initially, OPN was recognized as a cytokine with pro-inflammatory actions. More recently, OPN has emerged as a ... -
Exploring the interaction of quercetin-3-O-sophoroside with SARS-CoV-2 main proteins by theoretical studies: A probable prelude to control some variants of coronavirus including Delta
( Elsevier B.V. , 2021 , Article)The aim of this study was to investigate the mechanism of interaction between quercetin-3-O-sophoroside and different SARS-CoV-2?s proteins which can bring some useful details about the control of different variants of ... -
Current progress in chimeric antigen receptor T cell therapy for glioblastoma multiforme
( John Wiley and Sons Inc , 2021 , Article)Glioblastoma multiforme (GBM) is one of the deadliest brain tumors with an unfavorable prognosis and overall survival of approximately 20 months following diagnosis. The current treatment for GBM includes surgical resections ... -
Generation of gene edited hiPSC from familial Alzheimer's disease patient carrying N141I missense mutation in presenilin 2
( Elsevier B.V. , 2021 , Article)Alzheimer's disease (AD) is the major cause of dementia worldwide. Early-onset familial AD accounts for about 0.5% of all AD and is caused by single major gene mutations and autosomal dominant inheritance. An N141I missense ... -
Enzyme?polymeric/inorganic metal oxide/hybrid nanoparticle bio-conjugates in the development of therapeutic and biosensing platforms
( Elsevier B.V. , 2021 , Article)Background: Because enzymes can control several metabolic pathways and regulate the production of free radicals, their simultaneous use with nanoplatforms showing protective and combinational properties is of great interest ... -
An engineered microfluidic blood-brain barrier model to evaluate the anti-metastatic activity of β-boswellic acid
( John Wiley and Sons Inc , 2021 , Article)Background The development of anti-cancer drugs with the ability to inhibit brain metastasis through the blood-brain barrier (BBB) is substantially limited due to the lack of reliable in vitro models. Main Methods In ... -
Diagnostic and drug release systems based on microneedle arrays in breast cancer therapy
( Elsevier B.V. , 2021 , Article)Microneedle arrays have recently received much attention as cancer detection and treatment platforms, because invasive injections and detection of the biopsy are not needed, and drug metabolism by the liver, as well as ... -
Enhancement of mechanical and corrosion resistance properties of electrodeposited NiP-TiC composite coatings
( Nature Research , 2021 , Article)In the present study, the effect of concentration of titanium carbide (TiC) particles on the structural, mechanical, and electrochemical properties of Ni–P composite coatings was investigated. Various amounts of TiC particles ... -
3D printed nanocomposites for tailored cardiovascular tissue constructs: A minireview
( Elsevier B.V. , 2021 , Article)Cardiovascular diseases (CVD) with escalating death rates pose one of the greatest threats to global health and well-being. Thus, developing effective interventions to combat CVD are of critical importance. 3D printing ...