Mechanical & Industrial Engineering: Recent submissions
Now showing items 721-740 of 1396
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Irreversible thermal inactivation and conformational lock of alpha glucosidase
( Taylor and Francis Ltd. , 2021 , Article)In the present work, we studied the structure-activity relationship and kinetics of thermal inactivation of �-glucosidase A (AglA) in a 50 mM potassium phosphate buffer at pH 6.8 using p-nitrophenyl �-d-glucopyranoside ... -
Gold Nanoparticle-Based Platforms for Diagnosis and Treatment of Myocardial Infarction
( American Chemical Society , 2020 , Article)In recent years, an increasing rate of mortality due to myocardial infarction (MI) has led to the development of nanobased platforms, especially gold nanoparticles (AuNPs), as promising nanomaterials for diagnosis and ... -
Evaluation of angiogenic potential of heparin and thyroxine releasing wound dressings
( Taylor and Francis Ltd. , 2021 , Article)In the present research, heparin (1 ?g/ml, 5 ?g/ml) and thyroxine (1 ?g/ml, 5 ?g/ml) loaded wound dressings were prepared. Ultrastructure of the developed scaffolds revealed by scanning electron microscope and fourier ... -
Thermodynamic and anticancer properties of inorganic zinc oxide nanoparticles synthesized through co-precipitation method
( Elsevier B.V. , 2021 , Article)In this paper, inorganic zinc oxide nanoparticles (ZnO NPs) were synthesized through co-precipitation method and after evaluating their physicochemical properties by using TEM and XRD techniques, the bio-thermodynamic and ... -
3D Bioprinted cancer models: Revolutionizing personalized cancer therapy
( Neoplasia Press, Inc. , 2021 , Article)After cardiovascular disease, cancer is the leading cause of death worldwide with devastating health and economic consequences, particularly in developing countries. Inter-patient variations in anti-cancer drug responses ... -
Light-Controlled Growth Factors Release on Tetrapodal ZnO-Incorporated 3D-Printed Hydrogels for Developing Smart Wound Scaffold
( John Wiley and Sons Inc , 2021 , Article)Advanced wound scaffolds that integrate active substances to treat chronic wounds have gained significant recent attention. While wound scaffolds and advanced functionalities have previously been incorporated into one ... -
Fabrication of inorganic alumina particles at nanoscale by a pulsed laser ablation technique in liquid and exploring their protein binding, anticancer and antipathogenic activities
( Elsevier B.V. , 2021 , Article)The interaction of nanoparticles with biological systems can provide useful information about their therapeutic applications. The aluminum nanoparticles (Al2O3 NPs) were synthesized by laser ablation technique and ... -
Arabinoxylan/graphene-oxide/nHAp-NPs/PVA bionano composite scaffolds for fractured bone healing
( John Wiley and Sons Ltd , 2021 , Article)The importance of bone scaffolds has increased many folds in the last few years; however, during bone implantation, bacterial infections compromise the implantation and tissue regeneration. This work is focused on this ... -
Bone marrow mesenchymal stem cells preconditioned with nitric-oxide-releasing chitosan/PVA hydrogel accelerate diabetic wound healing in rabbits
( IOP Publishing Ltd , 2021 , Article)Impaired diabetic wounds are one of the major pathophysiological complications caused by persistent microbial infections, prolonged inflammation, and insufficient angiogenic responses. Here, we report the development of ... -
Development of biopolymeric hybrid scaffold-based on aac/go/nhap/tio2 nanocomposite for bone tissue engineering: In-vitro analysis
( MDPI AG , 2021 , Article)Bone tissue engineering is an advanced field for treatment of fractured bones to re-store/regulate biological functions. Biopolymeric/bioceramic-based hybrid nanocomposite scaffolds are potential biomaterials for bone ... -
Magnetic nanocatalysts as multifunctional platforms in cancer therapy through the synthesis of anticancer drugs and facilitated Fenton reaction
( Elsevier B.V. , 2021 , Article)Background: Heterocyclic compounds have always been used as a core portion in the development of anticancer drugs. However, there is a pressing need for developing inexpensive and simple alternatives to high-cost and complex ... -
Recent advances in 3D bioprinting of musculoskeletal tissues
( IOP Publishing Ltd , 2021 , Article)The musculoskeletal system is essential for maintaining posture, protecting organs, facilitating locomotion, and regulating various cellular and metabolic functions. Injury to this system due to trauma or wear is common, ... -
3D bioprinting of engineered breast cancer constructs for personalized and targeted cancer therapy
( Elsevier B.V. , 2021 , Article)The bioprinting technique with specialized tissue production allows the study of biological, physiological, and behavioral changes of cancerous and non-cancerous tissues in response to pharmacological compounds in personalized ... -
Bioengineered microfluidic blood-brain barrier models in oncology research
( Neoplasia Press, Inc. , 2021 , Article)Metastasis is the major reason for most brain tumors with up to a 50% chance of occurrence in patients with other types of malignancies. Brain metastasis occurs if cancer cells succeed to cross the ?blood-brain barrier? ... -
Active agents loaded extracellular matrix mimetic electrospun membranes for wound healing applications
( Editions de Sante , 2021 , Article)Achieving the healing of chronic diabetic ulcers, burn wounds and large traumatic wounds is a major clinical challenge. A variety of approaches have been undertaken to generate skin substitutes, wound healing patches or ... -
Development of nitric oxide releasing visible light crosslinked gelatin methacrylate hydrogel for rapid closure of diabetic wounds
( Elsevier Masson s.r.l. , 2021 , Article)Management of non-healing and slow to heal diabetic wounds is a major concern in healthcare across the world. Numerous techniques have been investigated to solve the issue of delayed wound healing, though, mostly unable ... -
Current progress in chimeric antigen receptor T cell therapy for glioblastoma multiforme
( John Wiley and Sons Inc , 2021 , Article)Glioblastoma multiforme (GBM) is one of the deadliest brain tumors with an unfavorable prognosis and overall survival of approximately 20 months following diagnosis. The current treatment for GBM includes surgical resections ... -
Stem cells based in vitro models: Trends and prospects in biomaterials cytotoxicity studies
( IOP Publishing Ltd , 2021 , Article)Advanced biomaterials are increasingly used for numerous medical applications from the delivery of cancer-targeted therapeutics to the treatment of cardiovascular diseases. The issues of foreign body reactions induced by ... -
Imaging cancer cells with nanostructures: Prospects of nanotechnology driven non-invasive cancer diagnosis
( Elsevier B.V. , 2021 , Article)The application of nanostructured materials in medicine is a rapidly evolving area of research that includes both the diagnosis and treatment of various diseases. Metals, metal oxides and carbon-based nanomaterials have ... -
Novel drug delivery systems based on triaxial electrospinning based nanofibers
( Elsevier B.V. , 2021 , Article)Electrospinning is a widely investigated process for forming nanofibers. Nanofibers in drug delivery systems are extensively tested due to its remarkable properties e.g. small pore size or large surface area. Recent articles ...
