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ASSESSMENT OF DIETARY HABITS, PHYSICAL ACTIVITY, LIFESTYLE, AND OTHER RISK FACTORS OF NONALCOHOLIC FATTY LIVER DISEASE AMONG ARAB ADULTS LIVING IN QATAR
(Human Nutrition, 2024 , Master Thesis)
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is defined as an abnormal accumulation of triglycerides in the liver. It is the most common chronic liver disease globally and is linked to ...
STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
(Medical Sciences, 2024 , Dissertation)
Homocystinuria, a rare disorder stemming from mutations in the CBS gene, results in cystathionine β-synthase (CBS) deficiency. CBS is a pivotal enzyme whose activity is enhanced by the allosteric regulator S-adenosylmethionine ...
COST-EFFECTIVENESS ANALYSIS OF SUBCUTANEOUS DARATUMUMAB VERSUS INTRAVENOUS DARATUMUMAB IN NEWLY DIAGNOSED MULTIPLE MYELOMA
(Pharmacy, 2024 , Master Thesis)
Background: Both subcutaneous (SC) and intravenous (IV) formulations of Daratumumab (Dara) are used, in combination with lenalidomide, bortezomib, and dexamethasone (VRd), for treating newly diagnosed multiple myeloma ...
CURCUMIN-CONJUGATED CHITOSAN OLIGOMERS DERIVED FROM MICROWAVE IRRADIATION FOR NANOFORMULATION IN COLON CANCER TREATMENT
(Pharmacy, 2024 , Master Thesis)
Colon cancer remains as one of the leading causes of deaths worldwide, whilst current treatment options are not optimal. Chemotherapy is the mainstay in cancer therapy but is associated with severe side effects. Some ...
IDENTIFICATION AND FUNCTIONAL VALIDATION OF RARE MISSENSE VARIANTS IN PLXNA1 AS A CANDIDATE GENE FOR SEVERE EARLY-ONSET OBESITY
(Biomedical Sciences, 2024 , Master Thesis)
Childhood obesity is a pressing issue in Qatar, with a reported prevalence of 49% among school-aged children and adolescents. This complex problem involves a combination of genetic and environmental factors. Monogenic ...
APPLICATION OF SOLID DISPERSION IN CONJUNCTION WITH 3D PRINTING FOR PERSONALIZED MEDICINE
(Pharmacy, 2024 , Master Thesis)
Poorly water-soluble drugs accounts for 40% of the newly discovered APIs due to their lipophilic nature. Hence, to benefit from the therapeutic effects of such drugs requires administration of higher doses. However, ...
RELATION BETWEEN BREAST MILK CONTENT OF TOTAL AFLATOXIN AND SOCIODEMOGRAPHIC AND NUTRITIONAL STATUS OF LACTATING MOTHERS IN QATAR
(Human Nutrition, 2024 , Master Thesis)
Background: Human milk is the ideal nourishment for neonates, as its unique nutritional composition supports adequate growth and development. On the other hand, human milk might contain contaminants including aflatoxins ...
Dissecting the Role of Physical Activity and Sleep in Metabolically Healthy Obese Subjects: A National Study
(Biomedical Sciences, 2024 , Master Thesis)
In the last decade, researchers brought attention to a subgroup of obesity that has a lower risk of cardiometabolic abnormalities. Considering Qatar is one of the top-ranked countries in terms of obesity, this study aims ...
CHARACTERIZATION OF PATHOGEN-ASSOCIATED ANTIBODY PROFILES IN DIABETES MELLITUS-TYPE 2 PATIENTS USING IMMUNOPROTEOMICS APPROACH
(Biomedical Sciences, 2024 , Master Thesis)
Type 2 diabetes mellitus (T2DM) is a common health concern globally. 80% of diabetic patients are T2DM patients. T2DM can result in many serious complications. For instance, cardiovascular diseases, renal diseases, eye ...
ASSOCIATION BETWEEN SOCIO-DEMOGRAPHICS AND NUTRITION KNOWLEDGE IN RELATION TO DIETARY ADHERENCE AND METABOLIC CONTROL IN HOMOCYSTINURIA PATIENTS IN QATAR
(Human Nutrition, 2024 , Master Thesis)
Classical Homocystinuria (HCU) is a metabolic disorder characterized by disrupted methionine metabolism, resulting in elevated homocysteine levels and potential organ complications. Understanding treatment adherence's ...