Student Thesis & Dissertations: Recent submissions
Now showing items 81-100 of 1594
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APPLICATION OF SOLID DISPERSION IN CONJUNCTION WITH 3D PRINTING FOR PERSONALIZED MEDICINE
(2024 , Master Thesis)Poorly water-soluble drugs accounts for 40% of the newly discovered APIs due to their lipophilic nature. Hence, to benefit from the therapeutic effects of such drugs requires administration of higher doses. However, ... -
COST-EFFECTIVENESS ANALYSIS OF SUBCUTANEOUS DARATUMUMAB VERSUS INTRAVENOUS DARATUMUMAB IN NEWLY DIAGNOSED MULTIPLE MYELOMA
(2024 , Master Thesis)Background: Both subcutaneous (SC) and intravenous (IV) formulations of Daratumumab (Dara) are used, in combination with lenalidomide, bortezomib, and dexamethasone (VRd), for treating newly diagnosed multiple myeloma ... -
STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
(2024 , Dissertation)Homocystinuria, a rare disorder stemming from mutations in the CBS gene, results in cystathionine β-synthase (CBS) deficiency. CBS is a pivotal enzyme whose activity is enhanced by the allosteric regulator S-adenosylmethionine ... -
THE EFFECT OF OBESITY ON RIVAROXABAN PHARMACOKINETICS AND PHARMACODYNAMICS
(2024 , Dissertation)Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a prevalent condition that is associated with high rates of morbidity and mortality worldwide. Similarly, atrial fibrillation ... -
CURCUMIN-CONJUGATED CHITOSAN OLIGOMERS DERIVED FROM MICROWAVE IRRADIATION FOR NANOFORMULATION IN COLON CANCER TREATMENT
(2024 , Master Thesis)Colon cancer remains as one of the leading causes of deaths worldwide, whilst current treatment options are not optimal. Chemotherapy is the mainstay in cancer therapy but is associated with severe side effects. Some ... -
Dissecting the Role of Physical Activity and Sleep in Metabolically Healthy Obese Subjects: A National Study
(2024 , Master Thesis)In the last decade, researchers brought attention to a subgroup of obesity that has a lower risk of cardiometabolic abnormalities. Considering Qatar is one of the top-ranked countries in terms of obesity, this study aims ... -
ASSESSMENT OF DIETARY HABITS, PHYSICAL ACTIVITY, LIFESTYLE, AND OTHER RISK FACTORS OF NONALCOHOLIC FATTY LIVER DISEASE AMONG ARAB ADULTS LIVING IN QATAR
(2024 , Master Thesis)Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is defined as an abnormal accumulation of triglycerides in the liver. It is the most common chronic liver disease globally and is linked to ... -
ANALYSIS OF MUTATIONS USING ANCIENT DNA GENOMES TO UNDERSTAND PATHOGENIC EMERGENCE AND DISEASE EVOLUTION
(2024 , Master Thesis)Paleogenomics, the study of ancient DNA, has revolutionized our comprehension of human history by providing access to genomic data spanning hundreds of thousands of years. High-throughput sequencing methods have enabled ... -
TRANSLATION AND ADAPTATION OF THE GENETIC COUNSELING OUTCOME SCALE (GCOS-24) FOR THE EVALUATION OF GENETIC COUNSELING SERVICES IN QATAR.
(2024 , Professional Masters Project)Background. The Genetic Counseling Outcome Scale (GCOS-24), introduced in the United Kingdom (UK) in 2011, is a theory-driven patient-reported outcome measure (PROM) developed for evaluating clinical genetics services. ... -
UNRAVELING THE MICROBIOME DIVERSITY AND DYNAMICS IN DIFFERENT SAMPLE TYPES DURING CORONAVIRUS INFECTIONS
(2024 , Master Thesis)Background: Mucosal immunity and gut microbiome influence respiratory diseases like those caused by coronaviruses (HCoV). This study explores the relationship between HCoV infection and the respiratory and gut microbiome. ... -
ASSOCIATION BETWEEN SOCIO-DEMOGRAPHICS AND NUTRITION KNOWLEDGE IN RELATION TO DIETARY ADHERENCE AND METABOLIC CONTROL IN HOMOCYSTINURIA PATIENTS IN QATAR
(2024 , Master Thesis)Classical Homocystinuria (HCU) is a metabolic disorder characterized by disrupted methionine metabolism, resulting in elevated homocysteine levels and potential organ complications. Understanding treatment adherence's ... -
PRENATAL WHOLE EXOME SEQUENCING OF FETAL SONOGRAPHIC ABNORMALITIES IN QATAR: DIAGNOSTIC YIELD AND GENETIC FINDINGS
(2024 , Professional Masters Project)Background: Fetal sonographic abnormalities at birth is estimated to be 2-3% of the global prevalence and are responsible for approximately 17%-42% of all perinatal deaths. Prenatal karyotype (KT) and chromosomal microarray ... -
ASSESSMENT OF GNAS LOSS OF FUNCTION IN MONOGENIC OBESITY USING THE ZEBRAFISH MODEL
(2024 , Master Thesis)GNAS (Guanine Nucleotide-Binding Protein, Alpha Stimulating) is an imprinted gene that encodes the alpha subunit of the stimulatory G protein (Gs), which participates in the signaling of various G protein-coupled receptors. ... -
THE USE OF SIMULATION GAMES AS A LEARNING TOOL AND ITS IMPACT ON STUDENTS' PERFROMANCE
(2024 , Professional Masters Project)The evolving landscape of education has witnessed a shift from traditional teaching methods to incorporate contemporary trends, such as the use of simulation games. This study explores the impact of simulation exercises ... -
A NEW APPROACH FOR WATER PURIFICATION USING GREEN NANOPARTICLES FABRICATED FROM THE LIME PEEL AS SILVER/COPPER NANOPARTICLES FOR THE "BISPHENOL A" REMEDIATION
(2024 , Master Thesis)One of the most common endocrine-disrupting compounds (EDCs) in the environment is bisphenol A (BPA), which has been linked to various chronic diseases. In light of these concerns, green synthesis of nanoparticles from ... -
ANTIBODY DEPENDENT ENHANCEMENT (ADE) - CAUSE OF DISEASE SEVERITY IN CORONAVIRUS INFECTED AND/OR VACCINATED INDIVIDUALS
(2024 , Master Thesis)Aim: This study evaluated the potential for ADE in serum samples from patients exposed to SARS-CoV-2 (Severe acute respiratory syndrome-coronavirus-2) and MERS-CoV (Middle East Respiratory Syndrome-coronavirus). For ... -
ESTABLISMENT, SURVIVAL AND RHIZOSPHERE MICROBIOME OF SELECTED PLANTS IRRIGATED BY GREYWATER FOR SUSTAINABLE URBAN GREENING
(2024 , Master Thesis)Appropriate control of water in suburban green spaces ends up critical as metropolitan populations grow and water shortage represents an urgent issue. This thesis looks at how certain plant species grown for the purpose ... -
THE EFFECT OF GENERATIVE AI ON STUDENTS' CREATIVE PROBLEM-SOLVING SKILLS
(2024 , Master Thesis)Higher Education Institutions (HEI) are assigned the responsibility of cultivating skillsets in students that improve their employability and maximize their value to industry. Creativity and problem-solving are important ... -
EXPLORING THE FACTORS THAT IMPACT THE DECISION TO START A NEW VENTURE: THE CASE OF WOMEN IN QATAR
(2024 , Professional Masters Project)As the female entrepreneur population in Qatar grows, their contributions to the economy have increased. Despite extensive research on general factors impacting entrepreneurial ventures, specific factors influencing female ... -
IMPACT OF MERGER AND ACQUISITION STRATEGIES ON BUSINESS GROWTH IN QATAR AND GLOBAL MARKETS
(2024 , Professional Masters Project)Increased globalization and competition in various industries has led to the rise of mergers and acquisitions for companies seeking competitive edge. The objective of this study is to investigate the impact of mergers and ...