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AuthorHassan, Hussein F.
AuthorKoaik, Lara
AuthorEl Khoury, André
AuthorAtoui, Ali
AuthorEl Obeid, Tahra
AuthorKaram, Layal
Available date2022-08-24T04:54:04Z
Publication Date2022-05-01
Publication NameToxins
Identifierhttp://dx.doi.org/10.3390/toxins14050331
CitationHassan, H.F.; Koaik, L.; Khoury, A.E.; Atoui, A.; El Obeid, T.; Karam, L. Dietary Exposure and Risk Assessment of Mycotoxins in Thyme and Thyme-Based Products Marketed in Lebanon. Toxins 2022, 14, 331. https://doi.org/10.3390/toxins14050331
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85130199474&origin=inward
URIhttp://hdl.handle.net/10576/33387
AbstractThis study aimed at evaluating the incidence of aflatoxin B1 (AFB1) and ochratoxin A (OTA) in thyme and thyme-based products, related dietary exposure, and cancer risk for regular and high consumption. A total of 160 samples were collected, and 32 composite samples were analyzed. AFB1 and OTA were respectively found in 84% (27/32) and 38% (12/32) of the samples. AFB1 exceeded the limits in 41% (13/32) and 25% (8/32) of the samples according to the Lebanese and European standards, respectively. OTA was unacceptable in only 6% (2/32) and 3% (1/32) of the samples according to the Lebanese and European standards, respectively. AFB1 and OTA daily exposure was shown to be 4.270 and 1.345 ng/kg bw/day, respectively. AFB1 was shown to be associated with 0.41 and 0.35 additional cancer cases per 100,000 persons per year for regular consumption, respectively; while for high consumption, an increase of 0.911 and 0.639 cancer cases per 100,000 person per year was noted, respectively. The margin of exposure (MOE) for OTA was >10,000 for the non-neoplastic effect and >200 for the neoplastic effect, representing no toxicological concerns for consumers.
Languageen
PublisherMDPI
SubjectAFB1
contamination
exposure
OTA
thyme
TitleDietary Exposure and Risk Assessment of Mycotoxins in Thyme and Thyme-Based Products Marketed in Lebanon
TypeArticle
Issue Number5
Volume Number14
ESSN2072-6651
dc.accessType Open Access


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