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AuthorAugustine, R.
AuthorAugustine, Robin
Available date2022-09-11T15:17:13Z
Publication Date2018-06-01
Publication NameProgress in Biomaterials
Identifierhttp://dx.doi.org/10.1007/s40204-018-0087-0
CitationAugustine, R. (2018). Skin bioprinting: a novel approach for creating artificial skin from synthetic and natural building blocks. Progress in biomaterials, 7(2), 77-92.‏
ISSN21940509
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85081710855&origin=inward
URIhttp://hdl.handle.net/10576/33829
AbstractSignificant progress has been made over the past few decades in the development of in vitro-engineered substitutes that mimic human skin, either as grafts for the replacement of lost skin, or for the establishment of in vitro human skin models. Tissue engineering has been developing as a novel strategy by employing the recent advances in various fields such as polymer engineering, bioengineering, stem cell research and nanomedicine. Recently, an advancement of 3D printing technology referred as bioprinting was exploited to make cell loaded scaffolds to produce constructs which are more matching with the native tissue. Bioprinting facilitates the simultaneous and highly specific deposition of multiple types of skin cells and biomaterials, a process that is lacking in conventional skin tissue-engineering approaches. Bioprinted skin substitutes or equivalents containing dermal and epidermal components offer a promising approach in skin bioengineering. Various materials including synthetic and natural biopolymers and cells with or without signalling molecules like growth factors are being utilized to produce functional skin constructs. This technology emerging as a novel strategy to overcome the current bottle-necks in skin tissue engineering such as poor vascularization, absence of hair follicles and sweat glands in the construct.
Languageen
PublisherSpringerOpen
SubjectBioprinting
Skin
Skin substitutes
Tissue engineering
Wound healing
TitleSkin bioprinting: a novel approach for creating artificial skin from synthetic and natural building blocks
TypeArticle Review
Issue Number2
Volume Number7
dc.accessType Open Access


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