تصفح Chemistry & Earth Sciences حسب المؤلف "Shkoor, Mohanad"
-
DMAP-Catalyzed Reaction of Diethyl 1,3-Acetonedicarboxylate with 2-Hydroxybenzylideneindenediones: Facile Synthesis of Fluorenone-Fused Coumarins
Shkoor, Mohanad; Bayari, Raghad ( Thieme Gruppe , 2021 , Other)The base-catalyzed reaction of diethyl 1,3-acetonedicarboxylate with 2-hydroxybenzylidene indenediones was studied. The reaction provides a facile and expeditious protocol for the synthesis of natural product inspired ... -
Integrated structural proteomics and machine learning-guided mapping of a highly protective precision vaccine against mycoplasma pulmonis
Abbas, Khan; Ammar Zahid, Muhammad; Farrukh, Farheen; Salah Abdelsalam, Shahenda; Mohammad, Anwar; Al-Zoubi, Raed M.; Shkoor, Mohanad; Ait Hssain, Ali; Wei, Dong-Qing; Agouni, Abdelali... more authors ... less authors ( Elsevier , 2024 , Article)Mycoplasma pulmonis (M. pulmonis) is an emerging respiratory infection commonly linked to prostate cancer, and it is classified under the group of mycoplasmas. Improved management of mycoplasma infections is essential due ... -
l-Proline-Catalyzed Three-Component Reaction of 4-Chloro-3-formylcoumarin, Sodium Sulfide, and α-Halo Ketones: A Direct Approach to Thieno[3,2- c ]coumarins
Thotathil, Vandana; Al-Zoubi, Raed M.; Sawali, Mona; Su, Haw Lih; Shkoor, Mohanad ( Georg Thieme Verlag KG , 2023 , Other)A new protocol for the synthesis of thieno[3,2-c]coumarins is disclosed. In this method, a 3-formyl-2-oxo-2H-chromene-4-thiolate anion is generated in situ by treatment of 4-chloro-3-formylcoumarin with sodium sulfide. ... -
Mechanochemical arylative detrifluoromethylation of trifluoromethylarenes
Mkrtchyan, Satenik; Shkoor, Mohanad; Sarfaraz, Sehrish; Ayub, Khurshid; Iaroshenko, Viktor O. ( Royal Society of Chemistry , 2023 , Article)The stoichiometric defluorinative functionalization of ArCF3 is a conceptually appealing research target. It enables the challenging late-stage functionalization of CF3-containing aromatic molecules and contributes to the ... -
Mechanochemical Conversion of Aromatic Amines to Aryl Trifluoromethyl Ethers
Jakubczyk, Michał; Mkrtchyan, Satenik; Shkoor, Mohanad; Lanka, Suneel; Budzák, Šimon; Iliaš, Miroslav; Skoršepa, Marek; Iaroshenko, Viktor O.... more authors ... less authors ( American Chemical Society , 2022 , Article)Increased interest in the trifluoromethoxy group in organic synthesis and medicinal chemistry has induced a demand for new, selective, general, and faster methods applicable to natural products and highly functionalized ... -
Mechanochemical Defluorinative Arylation of Trifluoroacetamides: An Entry to Aromatic Amides
Mkrtchyan, Satenik; Shkoor, Mohanad; Phanindrudu, Mandalaparthi; Medved′, Miroslav; Sevastyanova, Olena; Iaroshenko, Viktor O.... more authors ... less authors ( American Chemical Society , 2022 , Article)The amide bond is prominent in natural and synthetic organic molecules endowed with activity in various fields. Among a wide array of amide synthetic methods, substitution on a pre-existing (O)C-N moiety is an underexplored ... -
Mechanochemical Transformation of CF3 Group: Synthesis of Amides and Schiff Bases
Mkrtchyan, Satenik; Jakubczyk, Michał; Lanka, Suneel; Yar, Muhammad; Ayub, Khurshid; Shkoor, Mohanad; Pittelkow, Michael; Iaroshenko, Viktor O.... more authors ... less authors ( Wiley , 2021 , Article)We communicate two mild, solvent-free mechanochemical coupling transformations of CF3 group with nitro compounds into amides or Schiff bases employing Ytterbia as a catalyst. This process proceeds via C−F bond activation, ... -
Spectrofluorometric investigations on the solvent effects on the photocyclization reaction of diclofenac
Abdulilah Dawoud, Bani-Yaseen; Al-Zoubi, Raed M.; Shkoor, Mohanad ( Elsevier , 2023 , Article)The solvent effects on the photochemical conversion rate of the photosensitizing drug diclofenac (DCF) were investigated using steady-state fluorescence spectroscopy. The spectral information obtained for the photochemical ... -
Synthesis of 5-oxo-5H-chromeno[3,4-c]pyridine-1-carbonitriles and features of their NMR spectra
Shkoor, Mohanad; Su, Haw‐Lih; Ahmed, Suzan; Hegazy, Sarah ( Wiley , 2019 , Article)Two different methods leading to 5-oxo-5H-chromeno[3,4-c]pyridine-1-carbonitriles were investigated. Reactions of 3-aminocrotonirile with substituted salicylaldehydes provided 5-oxo-5H-chromeno[3,4-c]pyridine-1-carbonitriles ... -
Unusual product from the acid-catalyzed one-pot, multicomponent reaction of thiocarbohydrazide, aldehydes, and phenacyl bromides
Shkoor, Mohanad; Al-Abade, Ayahtallah; Aleteiwib, Ibtesam; Al-Talib, Mahmoud; Tashtoush, Hasan ( Taylor & Francis , 2017 , Article)A one-pot, three-component protocol for the synthesis of novel five-membered thiazole ring bonded to two hydrazone motifs is described. The acid-catalyzed reaction of one equivalent of thiocarbohydrazide, two equivalents ...