Browsing Research Units by Author "Fakhro, Khalid"
Now showing items 1-7 of 7
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Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers
Santosh K., Yadav; Gupta, Rakesh K.; Hashem, Sheema; Nisar, Sabah; Azeem, Taha; Bhat, Ajaz A.; Syed, Najeeb; Garg, Ravindra K.; Venkatesh, Vimala; Kamal, Madeeha; Fakhro, Khalid; Frenneaux, Michael P.; Haris, Mohammad... more authors ... less authors ( Elsevier , 2020 , Article)IntroductionAntiretroviral therapy (ART) is considered the most effective way to prevent perinatal transmission of human immunodeficiency virus (HIV). However, there is little knowledge about the effect of ART on the brain ... -
Genetic and Neuroimaging Approaches to Understanding Post-Traumatic Stress Disorder.
Nisar, Sabah; Bhat, Ajaz A; Hashem, Sheema; Syed, Najeeb; Yadav, Santosh K; Uddin, Shahab; Fakhro, Khalid; Bagga, Puneet; Thompson, Paul; Reddy, Ravinder; Frenneaux, Michael P; Haris, Mohammad... more authors ... less authors ( MDPI , 2020 , Article Review)Post-traumatic stress disorder (PTSD) is a highly disabling condition, increasingly recognized as both a disorder of mental health and social burden, but also as an anxiety disorder characterized by fear, stress, and ... -
Genetic variations influence brain changes in patients with attention-deficit hyperactivity disorder
Yadav, Santosh K.; Bhat, Ajaz A.; Hashem, Sheema; Nisar, Sabah; Kamal, Madeeha; Syed, Najeeb; Temanni, Mohamed Ramzi; Gupta, Rakesh K.; Kamran, Saddat; Azeem, Muhammad Waqar; Srivastava, Amit K.; Bagga, Puneet; Chawla, Sanjeev; Reddy, Ravinder; Frenneaux, Michael P.; Fakhro, Khalid; Haris, Mohammad... more authors ... less authors ( Springer Nature , 2021 , Article Review)Attention-deficit hyperactivity disorder (ADHD) is a neurological and neurodevelopmental childhood-onset disorder characterized by a persistent pattern of inattentiveness, impulsiveness, restlessness, and hyperactivity. ... -
Genetics of glutamate and its receptors in autism spectrum disorder
Nisar, Sabah; Bhat, Ajaz A.; Masoodi, Tariq; Hashem, Sheema; Akhtar, Sabah; Ali, Tayyiba Akbar; Amjad, Sara; Chawla, Sanjeev; Bagga, Puneet; Frenneaux, Michael P.; Reddy, Ravinder; Fakhro, Khalid; Haris, Mohammad... more authors ... less authors ( Springer Nature , 2022 , Article Review)Autism spectrum disorder (ASD) is a neurodevelopmental impairment characterized by deficits in social interaction skills, impaired communication, and repetitive and restricted behaviors that are thought to be due to altered ... -
Genetics of structural and functional brain changes in autism spectrum disorder.
Hashem, Sheema; Nisar, Sabah; Bhat, Ajaz A; Yadav, Santosh Kumar; Azeem, Muhammad Waqar; Bagga, Puneet; Fakhro, Khalid; Reddy, Ravinder; Frenneaux, Michael P; Haris, Mohammad... more authors ... less authors ( Springer Nature , 2020 , Article Review)Autism spectrum disorder (ASD) is a neurological and developmental disorder characterized by social impairment and restricted interactive and communicative behaviors. It may occur as an isolated disorder or in the context ... -
Qatar genome: Insights on genomics from the Middle East
Mbarek, Hamdi; Devadoss Gandhi, Geethanjali; Selvaraj, Senthil; Al-Muftah, Wadha; Badji, Radja; Al-Sarraj, Yasser; Saad, Chadi; Darwish, Dima; Alvi, Muhammad; Fadl, Tasnim; Yasin, Heba; Alkuwari, Fatima; Razali, Rozaimi; Aamer, Waleed; Abbaszadeh, Fatemeh; Ahmed, Ikhlak; Mokrab, Younes; Suhre, Karsten; Albagha, Omar; Fakhro, Khalid; Badii, Ramin; Ismail, Said I.; Althani, Asma... more authors ... less authors ( Wiley , 2022 , Article)Despite recent biomedical breakthroughs and large genomic studies growing momentum, the Middle Eastern population, home to over 400 million people, is underrepresented in the human genome variation databases. Here we ... -
Role of NAD+ in regulating cellular and metabolic signaling pathways
Sara, Amjad; Nisar, Sabah; Bhat, Ajaz A.; Shah, Ab Rauf; Frenneaux, Michael P.; Fakhro, Khalid; Haris, Mohammad; Reddy, Ravinder; Patay, Zoltan; Baur, Joseph; Bagga, Puneet... more authors ... less authors ( Elsevier , 2021 , Article Review)BackgroundNicotinamide adenine dinucleotide (NAD+), a critical coenzyme present in every living cell, is involved in a myriad of metabolic processes associated with cellular bioenergetics. For this reason, NAD+ is often ...