Browsing Research Units by Author "Elrayess, Mohamed A."
Now showing items 1-12 of 12
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Amniotic stem cells as a source of regenerative medicine to treat female infertility
Naeem, Aisha; Gupta, Nikita; Naeem, Usra; Elrayess, Mohamed A.; Albanese, Chris ( Springer , 2022 , Article Review)Impaired reproductive health is a worldwide problem that affects the psychological well-being of a society. Despite the technological developments to treat infertility, the global infertility rate is increasing significantly. ... -
Arrhythmia-Associated Calmodulin E105A Mutation Alters the Binding Affinity of CaM to a Ryanodine Receptor 2 CaM-Binding Pocket
Thanassoulas, Angelos; Theodoridou, Maria; Barrak, Laila; Riguene, Emna; Alyaarabi, Tamader; Elrayess, Mohamed A.; Lai, F. Anthony; Nomikos, Michail... more authors ... less authors ( MDPI , 2023 , Article)Calmodulin (CaM) is a small, multifunctional calcium (Ca2+)-binding sensor that binds and regulates the open probability of cardiac ryanodine receptor 2 (RyR2) at both low and high cytosolic Ca2+ concentrations. Recent ... -
Corrigendum: Association of Complement-Related Proteins in Subjects With and Without Second Trimester Gestational Diabetes (Front. Endocrinol., (2021), 12, (641361), 10.3389/fendo.2021.641361)
Ramanjaneya, Manjunath; Butler, Alexandra E.; Alkasem, Meis; Bashir, Mohammed; Jerobin, Jayakumar; Godwin, Angela; Moin, Abu Saleh Md; Ahmed, Lina; Elrayess, Mohamed A.; Hunt, Steven C.; Atkin, Stephen L.; Abou-Samra, Abdul Badi... more authors ... less authors ( Frontiers Media S.A. , 2021 , Other)In the original article, there was an error. One of the funders wasmissed out in the Acknowledgements. A correction has been made to the Acknowledgements section. “The authors would like to thank Qatar Metabolic Institute, ... -
Editorial: OMICS-Based Approaches in Sports Research.
Elrayess, Mohamed A; Botrè, Francesco; Palermo, Amelia ( Frontiers Media , 2022 , Other)Genomics, transcriptomics and metabolomics are increasingly generating key insights for the development of precision approaches in heath and disease. Omics technologies have unlocked the high-throughput discovery of ... -
Impact of Moderate Physical Activity on Inflammatory Markers and Telomere Length in Sedentary and Moderately Active Individuals with Varied Insulin Sensitivity
Almuraikhy, Shamma; Sellami, Maha; Al-Amri, Hadaia Saleh; Domling, Alexander; Althani, Asmaa A.; Elrayess, Mohamed A.... more authors ... less authors ( Dove Medical Press , 2023 , Article)Introduction: Physical activity-associated immune response plays a crucial role in the aging process. This study aimed to determine the impact of short-term moderate physical activity on cytokine levels, oxidative stress ... -
Mediators of Impaired Adipogenesis in Obesity-Associated Insulin Resistance and T2DM
Al-Sulaiti, Haya; Dömling, Alexander S.; Elrayess, Mohamed A ( IntechOpen , 2019 , Book chapter)Obesity has become a global health issue due to its high prevalence and associated comorbidities including insulin resistance (IR) and type 2 diabetes mellitus (T2DM). Obesity is associated with the expansion of adipose ... -
Metformin increases 3-hydroxy medium chain fatty acids in patients with type 2 diabetes: a cross-sectional pharmacometabolomic study
Naja, Khaled; Anwardeen, Najeha; Malki, Ahmed M.; Elrayess, Mohamed A. ( Frontiers Media SA , 2024 , Article)Background: Metformin is a drug with a long history of providing benefits in diabetes management and beyond. The mechanisms of action of metformin are complex, and continue to be actively debated and investigated. The aim ... -
Molecular regulators of exercise-mediated insulin sensitivity in non-obese individuals
Almuraikhy, Shamma; Doudin, Asmaa; Domling, Alexander; Althani, Asmaa Ali J.F.; Elrayess, Mohamed A. ( John Wiley and Sons Inc , 2023 , Article)Insulin resistance is a significant contributor to the development of type 2 diabetes (T2D) and is associated with obesity, physical inactivity, and low maximal oxygen uptake. While intense and prolonged exercise may have ... -
Protein tyrosine phosphatase 1B inhibition improves endoplasmic reticulum stress-impaired endothelial cell angiogenic response: A critical role for cell survival
ABDELSALAM, SHAHENDA S.; PASHA, MAZHAR; EL-GAMAL, HEBA; HASAN, MARAM; ELRAYESS, MOHAMED A.; ZEIDAN, ASAD; KORASHY, HESHAM M.; AGOUNI, ABDELALI... more authors ... less authors ( Spandidos publications , 2021 , Article)Endoplasmic reticulum (ER) stress contributes to endothelial dysfunction, which is the initial step in atherogenesis. Blockade of protein tyrosine phosphatase (PTP)1B, a negative regulator of insulin receptors that is ... -
The Relationship between Changes in MYBPC3 Single-Nucleotide Polymorphism-Associated Metabolites and Elite Athletes’ Adaptive Cardiac Function
Riguene, Emna; Theodoridou, Maria; Barrak, Laila; Elrayess, Mohamed A.; Nomikos, Michail ( MDPI , 2023 , Article Review)Athletic performance is a multifactorial trait influenced by a complex interaction of environmental and genetic factors. Over the last decades, understanding and improving elite athletes’ endurance and performance has ... -
The retrospective study of the metabolic patterns of BCG-vaccination in type-2 diabetic individuals in COVID-19 infection
Anwardeen, Najeha R.; Cyprian, Farhan S.; Yassine, Hadi M.; Al-Thani, Asmaa A.; Abdallah, Abdallah M.; Emara, Mohamed M.; Elrayess, Mohamed A.... more authors ... less authors ( Frontiers Media , 2023 , Article)Background: The cross-protective nature of Bacillus Calmette-Guerin (BCG) vaccine against SARS-CoV-2 virus was previously suggested, however its effect in COVID-19 patients with type 2 diabetes (T2D) and the underlying ... -
Statistical methods and resources for biomarker discovery using metabolomics.
Anwardeen, Najeha R; Diboun, Ilhame; Mokrab, Younes; Althani, Asma A; Elrayess, Mohamed A ( BMC , 2023 , Article Review)Metabolomics is a dynamic tool for elucidating biochemical changes in human health and disease. Metabolic profiles provide a close insight into physiological states and are highly volatile to genetic and environmental ...