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Now showing items 1271-1280 of 1343
Effectiveness of two and three doses of COVID-19 mRNA vaccines against infection, symptoms, and severity in the pre-omicron era: A time-dependent gradient
(
Elsevier
, 2024 , Article)
BackgroundVaccines were developed and deployed to combat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This study aimed to characterize patterns in the protection provided by the BNT162b2 and ...
Pathogenic Homocystinuria-Associated T236N Mutation Dramatically Alters the Biochemical Properties of Cystathionine Beta-Synthase Protein
(
MDPI
, 2024 , Article)
Background: Cystathione beta-synthase (CBS) T236N is a novel mutation associated with pyridoxine non-responsiveness, which presents a significant difficulty in the medical treatment of homocystinuria. Reported severe ...
SARS-CoV-2 infection triggers more potent antibody-dependent cellular cytotoxicity (ADCC) responses than mRNA-, vector-, and inactivated virus-based COVID-19 vaccines
(
Wiley
, 2024 , Article)
Neutralizing antibodies (NAbs) are elicited after infection and vaccination and have been well studied. However, their antibody-dependent cellular cytotoxicity (ADCC) functionality is still poorly characterized. Here, we ...
Development of Recombinant PLC-Zeta Protein as a Therapeutic Intervention for the Clinical Treatment of Oocyte Activation Failure
(
MDPI
, 2024 , Article)
The sperm-specific phospholipase C zeta (PLCζ) protein is widely considered as the predominant physiological stimulus for initiating the Ca2+ release responsible for oocyte activation during mammalian fertilization. The ...
Validation and application of a membrane filtration evaluation protocol for oil-water separation
(
Elsevier Ltd
, 2021 , Article)
Membrane filtration processes like microfiltration (MF) and ultrafiltration (UF) are proven to be effective in industrial wastewater treatment, including oil-water separation, as they generate suitable quality permeate for ...
Environmental Drivers of Habitat Use by Hawksbill Turtles (Eretmochelys imbricata) in the Arabian Gulf (Qatar)
(
Frontiers Media SA
, 2020 , Article)
Understanding the environmental drivers of movement patterns are critical to the protection, management and recovery of endangered species. The Arabian Gulf is considered to be the hottest marine system in the world and ...
Performance evaluation of novel fluorescent-based lateral flow immunoassay (LFIA) for rapid detection and quantification of total anti-SARS-CoV-2 S-RBD binding antibodies in infected individuals
(
Elsevier
, 2022 , Article)
The vast majority of the commercially available LFIA is used to detect SARS-CoV-2 antibodies qualitatively. Recently, a novel fluorescence-based LIFA test was developed for quantitative measurement of the total binding ...
A comprehensive review on harvesting of microalgae using Polyacrylamide-Based Flocculants: Potentials and challenges
(
Elsevier
, 2021 , Article)
Microalgae biomass is touted as a highly promising source of renewable third-generation biofuels that could enable a lucrative transition from conventional fossil fuels to more sustainable and environment-friendly energy ...
Frugal innovation and sustainable business models
(
Elsevier
, 2021 , Article)
This study aims to explore how frugal innovations (FIs) emerge at the grassroots level of developing countries and employ novel business models to contribute to sustainable development. It explores various business model ...
Frugal innovation: Unveiling the uncomfortable reality
(
Elsevier
, 2021 , Article)
Frugal innovation (FI) has been getting growing attention from scholars, practitioners, and policymakers for its promise to serve low-income customers with affordable solutions. As a recently emerged concept, it has been ...