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Human Olfactory Bulb Neural Stem Cells Expressing hNGF Restore Cognitive Deficit in Alzheimer's Disease Rat Model
(
Wiley
, 2015 , Article)
In this study, we aim to demonstrate the fate of allogenic adult human olfactory bulb neural stem/progenitor cells (OBNSC/NPCs)
transplanted into the rat hippocampus treated with ibotenic acid (IBO), a neurotoxicant ...
Detection and Phylogenetic Analysis of Human Pegivirus (GBV-C) Among Blood Donors and Patients Infected With Hepatitis B Virus (HBV) in Qatar
(
Wiley
, 2015 , Article)
Human Pegivirus (HPgV), formerly GB virus-C/
Hepatitis G virus (GBV-C/HGV), collectively
known as GBV-C, is widely spread and has
been reported to be associated with non-A–E
hepatitis. To our knowledge, no previous ...
Therapeutic potential of human olfactory bulb neural stem cells for spinal cord injury in rats.
(
Nature Publishing Group
, 2016 , Article)
STUDY DESIGN:
Adult human olfactory bulb neural stem cells (OBNSCs) were isolated from human patients undergoing craniotomy for tumor resection. They were genetically engineered to overexpresses green fluorescent protein ...
Pseudomonas aeruginosa: arsenal of resistance mechanisms, decades of changing resistance profiles, and future antimicrobial therapies.
(
Future Medicine
, 2015 , Article)
Antimicrobial resistance is one of the most serious public health issues facing humans since the discovery of antimicrobial agents. The frequent, prolonged, and uncontrolled use of antimicrobial agents are major factors ...
Common and Rare Genetic Variants Associated With Alzheimer's Disease
(
WILEY PERIODICALS, INC.
, 2016 , Article)
Alzheimer's disease (AD) is one of the most devastating disorders. Despite the continuing increase of its incidence among aging populations, no effective cure has been developed mainly due to difficulties in early diagnosis ...
PDGFRα depletion attenuates glioblastoma stem cells features by modulation of STAT3, RB1 and multiple oncogenic signals.
(
Impact Journals
, 2016 , Article)
Platelet derived growth factor receptors (PDGFRs) play an important role in tumor pathogenesis, and they are frequently overexpressed in glioblastoma (GBM). Earlier we have shown a higher protein expression of PDGFR isoforms ...
Pre-fusion structure of a human coronavirus spike protein
(
Nature Publishing Group
, 2015 , Article)
HKU1 is a human betacoronavirus that causes mild yet prevalent
respiratory disease1, and is related to the zoonotic SARS2 and
MERS3 betacoronaviruses, which have high fatality rates and
pandemic potential. Cell tropism ...
2022 Qatar World Cup: Impact Perceptions among Qatar Residents
(
SAGE Publications
, 2016 , Article)
The purpose of this study was to evaluate how the impacts from the 2022 World Cup preparations in Qatar influenced local
residents’ attitudes, personal and community quality of life perceptions, excitement about hosting ...
"Protecting" or "policing": Academic researchers' view of IRBs in an arab context
(
SAGE Publications Inc.
, 2014 , Article)
A recent surge of research universities and human subjects research funding in the Arab world raises concerns about applied research ethics and oversight. In-depth interviews conducted with 52 researchers in Lebanon and ...
Within-Household Sampling Conditioning on Household Size
(
Published by Oxford University Press on behalf of The World Association
, 2012 , Article)
We review existing methods for sampling an adult from a household and highlight the strengths and weaknesses of these methods with respect to issues relevant for sampling in the Middle East and developing countries. We ...