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Trends in fecal carriage of carbapenemase-producing Enterobacterales in children before and after the implementation of international travel restrictions in response to COVID-19
(
Elsevier
, 2021 , Other)
Qatar is located on the northeast coast of the Arabian Peninsula with a large expatriate population comprising 86% of the country's population, most of whom originate from Indian subcontinent countries [1]. International ...
Antibiotics Prescribing in Intensive Care Settings during the COVID-19 Era: A Systematic Review
(
MDPI
, 2021 , Article)
The prevalence of patients admitted to intensive care units (ICUs) with SARS-CoV-2
infection who were prescribed antibiotics is undetermined and might contribute to the increased
global antibiotic resistance. This ...
Reinfections in COVID-19 Patients: Impact of Virus Genetic Variability and Host Immunity
(
MDPI
, 2021 , Article)
The COVID-19 pandemic is still posing a devastating threat to social life and economics. Despite the modest decrease in the number of cases during September-November 2020, the number of active cases is on the rise again. ...
Molecular and Biological Mechanisms Underlying Gender Differences in COVID-19 Severity and Mortality
(
Frontiers Media
, 2021 , Article)
Globally, over two million people have perished due to the recent pandemic caused by SARS-CoV-2. The available epidemiological global data for SARS-CoV-2 portrays a higher rate of severity and mortality in males. Analyzing ...
One Year of SARS-CoV-2: Genomic Characterization of COVID-19 Outbreak in Qatar
(
Frontiers
, 2021 , Article)
Qatar, a country with a strong health system and a diverse population consisting mainly of expatriate residents, has experienced two large waves of COVID-19 outbreak. In this study, we report on 2634 SARS-CoV-2 whole-genome ...
Detection of SARS-CoV-2 RNA by direct RT-qPCR on nasopharyngeal specimens without extraction of viral RNA.
(
Public Library of Science
, 2020 , Article)
To circumvent the limited availability of RNA extraction reagents, we aimed to develop a protocol for direct RT-qPCR to detect SARS-CoV-2 in nasopharyngeal swabs without RNA extraction. Nasopharyngeal specimens positive ...
Identification of potential natural inhibitors of the receptor-binding domain of the SARS-CoV-2 spike protein using a computational docking approach
(
Hamad Bin Khalifa University Press
, 2021 , Article)
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the only zoonotic-origin CoV to reach the pandemic stage, to which neither an effective vaccine nor a specific therapy is available. The spike ...
Repurposing Ivermectin for COVID-19: Molecular Aspects and Therapeutic Possibilities
(
Frontiers Media
, 2021 , Article)
As of January 2021, SARS-CoV-2 has killed over 2 million individuals across the world. As such, there is an urgent need for vaccines and therapeutics to reduce the burden of COVID-19. Several vaccines, including mRNA, ...
COVID-19 Vaccination: The Mainspring of Challenges and the Seed of Remonstrance
(
MDPI
, 2021 , Article Review)
As of March 2020, the time when the coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) became a pandemic, our existence has been threatened and the lives of ...