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GATA-3 as a potential therapeutic target for insulin resistance and type 2 diabetes mellitus.
(
PubMed Central
, 2020 , Article Review)
Impaired adipogenesis plays an important role in the development of obesity-associated insulin resistance and type 2 diabetes as it leads to ectopic fat deposition. The anti-adipogenic transcription factor GATA-3 was ...
Suppression of GATA-3 increases adipogenesis, reduces inflammation and improves insulin sensitivity in 3T3L-1 preadipocytes
(
Elsevier
, 2020 , Article)
© 2020 Impaired adipogenesis plays an important role in the development of obesity-associated insulin resistance and type 2 diabetes. Adipose tissue inflammation is a crucial mediator of this process. GATA-3 plays important ...
Letrozole-loaded nonionic surfactant vesicles prepared via a slurry-based proniosome technology: Formulation development and characterization
(
Elsevier
, 2020 , Article)
Slurry-based Letrozole (LTZ)-loaded proniosomes were designed using sucrose or sorbitol as carriers and various ratios of cholesterol (CH) and Tween 80 (T80) as lipid composition. Proniosomes were hydrated and probe-sonicated ...
Metabolomics and doping analysis: promises and pitfalls.
(
Future Science
, 2020 , Article)
This brief commentary presents an overview of the potential utility of metabolomics-based approaches in doping
analysis, with particular emphasis on areas where the current analytical procedures would most benefit from ...
Metabolic profiling of elite athletes with different cardiovascular demand
(
John Wiley & Sons Ltd
, 2019 , Article)
Intensive exercise of elite athletes can lead to physiological alterations in the cardiovascular system in response to increased stroke volume and blood pressure, known collectively as cardiovascular demand (CD). This study ...
Evaluation of the Influence of Eggshell (ES) Concentration on the Degradation Behavior of Mg–2.5Zn Biodegradable Alloy in Simulated Body Fluid
(
American Chemical Society (ACS)
, 2023 , Article)
Currently, permanent vascular stents are fabricated using titanium and stainless steel implants that are nondegradable and offer high stability, but they have certain disadvantages. For example, the prolonged exposition ...
Protein tyrosine phosphatase 1B inhibition improves endoplasmic reticulum stress-impaired endothelial cell angiogenic response: A critical role for cell survival
(
Spandidos publications
, 2021 , Article)
Endoplasmic reticulum (ER) stress contributes to endothelial dysfunction, which is the initial step in atherogenesis. Blockade of protein tyrosine phosphatase (PTP)1B, a negative regulator of insulin receptors that is ...