Search
Now showing items 1-4 of 4
Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk.
(
Frontiers Media
, 2019 , Article)
The ability of epithelial cells to organize through cell-cell adhesion into a functioning epithelium serves the purpose of a tight epithelial protective barrier. Contacts between adjacent cells are made up of tight junctions ...
Claudin-1, A Double-Edged Sword in Cancer.
(
MDPI
, 2020 , Article Review)
Claudins, a group of membrane proteins involved in the formation of tight junctions, are mainly found in endothelial or epithelial cells. These proteins have attracted much attention in recent years and have been implicated ...
Decoding the functional role of extracellular vesicles in hepatocellular carcinoma: implications in clinical theranostics
(
Elsevier
, 2022 , Book chapter)
Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer in adults, the sixth most commonly diagnosed neoplasia, and the third leading cause of cancer-related deaths worldwide. Despite tangible ...
Cytokine- and chemokine-induced inflammatory colorectal tumor microenvironment: Emerging avenue for targeted therapy
(
Wiley
, 2022 , Article Review)
Colorectal cancer (CRC) is a predominant life-threatening cancer, with liver and peritoneal metastases as the primary causes of death. Intestinal inflammation, a known CRC risk factor, nurtures a local inflammatory environment ...