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Glycan repositioning of influenza hemagglutinin stem facilitates the elicitation of protective cross-group antibody responses.
(
Nature Research
, 2020 , Article)
The conserved hemagglutinin (HA) stem has been a focus of universal influenza vaccine efforts. Influenza A group 1 HA stem-nanoparticles have been demonstrated to confer heterosubtypic protection in animals; however, the ...