Research Units: Recent submissions
Now showing items 281-300 of 5213
-
In-vivo pharmacokinetic study of ibrutinib-loaded nanostructured lipid carriers in rat plasma by sensitive spectrofluorimetric method using harmonized approach of quality by design and white analytical chemistry
( Elsevier , 2024 , Article)Ibrutinib, an antineoplastic agent tackling chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom’s Macroglobulinemia, falls under the category of BCS class II drugs, characterized by a puzzling combination ... -
Targeting protein receptors and enzymes for precision management of urolithiasis: A comprehensive review
( Elsevier , 2024 , Article)Urolithiasis, characterized by the formation of solid crystalline structures within the urinary tract, presents a significant global health burden with high recurrence rates and limited treatment efficacy. Recent research ... -
Development of novel nanoemulsion of pioglitazone used in the treatment of diabetes and its gel form for the treatment of skin diseases
( Elsevier , 2024 , Article)Pioglitazone (PGL), an antidiabetic drug within the thiazolidinedione class, is utilized in managing type-2-diabetes-mellitus. Additionally, it has been observed to exhibit therapeutic effects on various inflammatory ... -
A novel mucoadhesive paliperidone-nanoemulsion developed using the ultrasonication method in the treatment of schizophrenia
( Royal Society of Chemistry , 2024 , Article)Aim: To develop paliperidone mucoadhesive-nanoemulsion (PLP-NE) to enhance brain bioavailability. To evaluate comparative effects of PLP-NE and CS-PLP-NE in the treatment of schizophrenia, followed by a toxicity study of ... -
In-Vitro Dissolution Study of Solid Dispersion Adsorbate of Nateglinide by Eco-Friendly Liquid Chromatography-Tandem Mass Spectrometric Method through Harmonized Approach of White Analytical Chemistry and Analytical Quality by Design
( Springer Nature , 2024 , Article)Purpose: Nateglinide, a member of the meglitinide class, is used as an oral antihyperglycemic agent to treat non-insulin-dependent diabetes mellitus. It falls under the BCS class II category and has a low solubility ... -
Ziziphus nummularia crude and fractionated extracts attenuate the malignant phenotype of human triple-negative breast cancer cells
( Symposium Cracoviense , 2024 , Conference Paper)Triple negative breast cancer (TNBC) is the most aggressive subtype of breast cancer and has limited therapeutic options. Effects of Ziziphus nummularia against TNBC have not been investigated yet. An ethanolic extract of ... -
Comparable antibody levels in heterologous and homologous mRNA COVID-19 vaccination, with superior neutralizing and IgA antibody responses in mRNA homologous boosting
( Elsevier , 2024 , Article)BackgroundPriming with two doses of AZD1222 (Oxford-AstraZeneca; ChAd) followed by a third mRNA vaccine boosting is considered in several countries, yet comparisons between heterologous and homologous booster efficacy ... -
Prevalence of hepatitis A virus among migrant workers in Qatar: A national study
( Public Library of Science , 2024 , Article)Background Hepatitis A virus (HAV) is the predominant cause of acute viral hepatitis worldwide; however, data on HAV antibody prevalence (seroprevalence) among migrant populations are limited. This study aimed to investigate ... -
A Terpenoid-Rich Fraction of Inula viscosa: Its Chemical Composition, Antioxidant Capacity, and Anticancerous Effects Against Human Lung Cancer Cells
( Preprints , 2024 , Article)Inula viscosa is a widely used plant in traditional Mediterranean and Middle Eastern medicine for various illnesses. I. viscosa has been shown to have anticancerous effects against various cancers, but its effects against ... -
Barriers to formal volunteering among married Qatari youth
( Springer Nature , 2024 , Article)Purpose: This paper aims to identify key factors influencing the lack of formal volunteering among married Qatari youth. Methodology: Utilizing data from the Qatar Youth Survey with a sample of 598 married individuals, ... -
Clinical reappraisal of the composite international diagnostic interview version 3.3 in Qatar's National Mental Health Study
( Wiley , 2024 , Article)Objectives: Lifetime DSM-5 diagnoses generated by the lay-administered Composite International Diagnostic Interview for DSM-5 (CIDI) in the World Mental Health Qatar (WMHQ) study were compared to diagnoses based on blinded ... -
Predictive Machine Learning Algorithms for Metro Ridership Based on Urban Land Use Policies in Support of Transit-Oriented Development
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)The endeavors toward sustainable transportation systems are a key concern for planners and decision-makers where increasing public transport attractiveness is essential. In this paper, a machine-learning-based predictive ... -
A Data-Driven Approach to Assessing Digital Transformation Maturity Factors in Government Institutes
( IEEE , 2023 , Conference Paper)Governments around the world are increasingly using digital transformation to improve their services and operations. Digital maturity assessment models however are mainly designed for business organizations, and there are ... -
A General Framework for Building Resilient Global Supply Chains
( IEEE , 2023 , Conference Paper)With the rapid globalization and expansion of supply chains, the risk of disruptions has increased, leading to severe financial losses and operational shutdowns. The pursuit of global integration and efficiency has further ... -
Trilemma of life cycle carbon, employment, and costs of trucking industry's shift toward automation and electrification
( John Wiley and Sons Inc , 2024 , Article)The transportation sector is undergoing a transformative shift, driven by advancements like autonomous and electric vehicle technologies. In this research, we investigate employment, carbon emissions, and total cost of ... -
Life cycle sustainability assessment of emerging mobility technologies: Perspective, challenges, and future directions
( Edward Elgar Publishing Ltd. , 2024 , Book chapter)Emerging mobility technologies come with uncertainties in terms of their social, economic, and environmental impacts. Considering the potential impacts of emerging transportation systems, life cycle sustainability assessment ... -
Chemical Composition, Antioxidant Capacity, and Anticancerous Effects against Human Lung Cancer Cells of a Terpenoid-Rich Fraction of Inula viscosa
( MDPI , 2024 , Article)Inula viscosa is a widely used plant in traditional Mediterranean and Middle Eastern medicine for various illnesses. I. viscosa has been shown to have anticancer effects against various cancers, but its effects against ... -
Breathing Clean Air: Navigating Indoor Air Purification Techniques and Finding the Ideal Solution
( MDPI , 2024 , Article)The prevalence of airborne pathogens in indoor environments presents significant health risks due to prolonged human occupancy. This review addresses diverse air purification systems to combat airborne pathogens and the ... -
Qatar's National Mental Health Survey—The World Mental Health Qatar: Sampling design, instrument adaptation, quality control, and fielding procedures
( John Wiley & Sons Ltd. , 2024 , Article)Objectives: The World Mental Health Qatar (WMHQ) study, the first national general population mental health survey in Qatar, was conducted as part of the World Health Organization (WHO) World Mental Health (WMH) Survey ... -
How Chinese Companies are Dominating Electric Vehicle Market Worldwide
( UC Berkeley Haas School of Business , 2024 , Other)An EV car is a vehicle powered by an electric motor, using energy stored in rechargeable batteries. It offers a cleaner alternative to gasoline or diesel engines, reducing greenhouse gas emissions and dependency on fossil ...
