College of Arts & Sciences: Recent submissions
Now showing items 981-1000 of 3700
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Salinomycin induces apoptosis and senescence in breast cancer: Upregulation of p21, downregulation of survivin and histone H3 and H4 hyperacetylation
( Elsevier , 2013 , Article)Background In the present study, we investigated the effect of Salinomycin on the survival of three human breast cancer cell lines MCF-7, T47D and MDA-MB-231 grown in adherent culture conditions. Methods Cell viability ... -
Cyclic AMP-Rap1A signaling mediates cell surface translocation of microvascular smooth muscle α2C-adrenoceptors through the actin-binding protein filamin-2
( American Physiological Society , 2013 , Article)The second messenger cyclic AMP (cAMP) plays a vital role in vascular physiology, including vasodilation of large blood vessels. We recently demonstrated cAMP activation of Epac-Rap1A and RhoA-Rho-associated kinase ... -
Cyclic AMP-Rap1A signaling activates RhoA to induce α2c-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells
( American Physiological Society , 2012 , Article)Intracellular signaling by the second messenger cyclic AMP (cAMP) activates the Ras-related small GTPase Rap1 through the guanine exchange factor Epac. This activation leads to effector protein interactions, activation, ... -
Anti-atherosclerotic plants which modulate the phenotype of vascular smooth muscle cells
( Elsevier , 2016 , Article)Background: Cardiovascular disease (CVD) remains the leading cause of global death, with atherosclerosis being a major contributor to this mortality. Several mechanisms are implicated in the pathogenesis of this disease. ... -
Determination of vascular reactivity of middle cerebral arteries from stroke and spinal cord injury animal models using pressure myography
( Humana Press Inc. , 2016 , Book chapter)Stroke and other neurovascular derangements are main causes of global death. They, along with spinal cord injuries, are responsible for being the principal cause of disability due to neurological and cognitive problems. ... -
Thymus vulgaris (Thyme) inhibits proliferation, adhesion, migration, and invasion of human colorectal cancer cells
( Mary Ann Liebert Inc. , 2015 , Article)Colorectal cancer (CRC) remains one of the most common malignancies and a leading cause of cancer-related deaths. Its prognosis remains poor for patients with several grades of this disease. This underscores the need for ... -
The impact of COVID-19 pandemic on electricity consumption and electricity demand forecasting accuracy: Empirical evidence from the state of Qatar
( Elsevier Ltd , 2022 , Article)The goal of this study is to use machine-learning (ML) techniques and empirical big data to examine the influence of the COVID-19 pandemic on electricity usage and electricity demand forecasting accuracy in buildings in ... -
المسلمون والنصارى : قراءة في مبدأ المعاملة بالمثل في سياق العلاقات التونسية الغربية خلال القرن الثامن عشر
( مؤسسة التميمي للبحث العلمي والمعلومات , 2023 , Article)دأبت الأدبيات الأوربية والوثائق الدبلوماسية خلال العصر الحديث على وسم المسلمين شرقا وغربا بعبارة أتباع "محمد Mohametans لاسيما في إطار العلاقات الثنائية التي جمعت بين المسلمين والنصارى ، أو في إطار التعرف على "الآخر المسلم". ... -
Hermite-Hadamard and Fejer-type inequalities for generalized η-convex stochastic processes
( Taylor and Francis Ltd. , 2023 , Article)In this article, we introduce the concept of (Formula presented.) -convex stochastic processes on coordinates and establish Hermite-Hadamard-type inequality for these stochastic processes. Moreover, we prove new integral ... -
Some new integral inequalities for higher-order strongly exponentially convex functions
( Institute for Ionics , 2023 , Article)Integral inequalities with generalized convexity play an important role in both applied and theoretical mathematics. The theory of integral inequalities is currently one of the most rapidly developing areas of mathematics ... -
Two-factor Heston model equipped with regime-switching: American option pricing and model calibration by Levenberg-Marquardt optimization algorithm
( Elsevier B.V. , 2023 , Article)In this paper, we consider the pricing of American options under a regime-switching double Heston model, such that the interest rate and mean-reversion level parameters in both stochastic volatility models shift in various ... -
Hermite-Hadamard type integral inequalities for multidimensional general h-harmonic preinvex stochastic processes
( Taylor and Francis Ltd. , 2022 , Article)In this paper, we introduce a new concept of preinvex functions which is called general h-harmonic preinvex for real-valued stochastic processes. Further, we define the multidimensional general h-harmonic preinvex stochastic ... -
A penalty decomposition algorithm for the extended mean-variance-CVaR portfolio optimization problem
( World Scientific , 2023 , Article)In this paper, we study mean-variance-Conditional Value-At-Risk (CVaR) portfolio optimization problem with short selling, cardinality constraint and transaction costs. To tackle its mixed-integer quadratic optimization ... -
Penalty ADM Algorithm for Cardinality Constrained Mean-Absolute Deviation Portfolio Optimization
( International Academic Press , 2022 , Article)In this paper, we study the cardinality constrained mean-absolute deviation portfolio optimization problem with risk-neutral interest rate and short-selling. We enhance the model by adding extra constraints to avoid investing ... -
On strongly generalized convex stochastic processes
( Taylor and Francis Ltd. , 2022 , Article)In this paper, we introduce the notion of strongly generalized convex functions which is called as strongly η-convex stochastic processes. We prove the Hermite-Hadamard, Ostrowski type inequality, and obtain some important ... -
Large-scale global optimization based on hybrid swarm intelligence algorithm
( IOS Press , 2020 , Article)There are numerous large-scale global optimization problems encountered in real-world applications including engineering, manufacturing, economics, networking fields. Over the last two decades different varieties of swarm ... -
A weighted version of Hermite-Hadamard type inequalities for strongly GA-convex functions
( Institute of Advanced Science Extension (IASE) , 2020 , Article)In this paper, we have established new weighted Hermite-Hadamard type inequalities for strongly GA-convex functions. Those findings are obtained by using geometric symmetry of continuous positive mappings and differentiable ... -
The common solutions of the split feasibility problems and fixed point problems
( Springer International Publishing , 2015 , Article)An extraordinary split problem, which can be regarded as a superimposition of the split feasibility problem and the split fixed point problem, is considered. A superimposed algorithm is presented. The analysis technique ... -
Optimal Production Planning Strategy for Deteriorating Items in Terms of Emission Tax, Pollution, and R&D Investment
( Springer Science and Business Media B.V. , 2018 , Conference)Firms are faced with the question of what policies to implement to ensure efficient abatement behavior? In this paper, we aim to determine the optimal production rate and the optimal investment rate in pollution abatement ... -
Entropy-Like Minimization Methods Based on Modified Proximal Point Algorithm
( University of Toronto Press Inc. , 2014 , Article)In this paper we introduce an extension of the proximal point algorithm proposed by Guler for solving convex minimization problems. This extension is obtained by substituting the usual quadratic proximal term by a class ...
