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Predictors for hospital admission in emergency department patients with benign paroxysmal positional vertigo: A retrospective review.
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Public Library of Science
, 2023 , Article)
This study aims to assess the incidence of Emergency Department (ED) visits for benign paroxysmal positional vertigo (BPPV), describe patient characteristics, management practices and predictors of inpatient admission of ...
Natural resorcylic acid lactones: A chemical biology approach for anticancer activity
(
Elsevier
, 2022 , Article)
Resorcylic acid lactones (RALs) are fungal polyketides that consist of a β-resorcylic acid residue (2,4-dihydroxybenzoic acid) embedded in a macrolactone ring. RALs exhibit a broad range of biological activities, including ...
Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells
(
Elsevier
, 2022 , Article)
Neosetophomone B (NSP–B), a meroterpenoid fungal secondary metabolite, was investigated for its anticancer potential in leukemic cell lines (K562 and U937). NSP-B treatment of leukemic cells suppressed cell viability by ...
Peri-renal adipose inflammation contributes to renal dysfunction in a non-obese prediabetic rat model: Role of anti-diabetic drugs
(
Elsevier
, 2021 , Article)
Diabetic nephropathy is a major health challenge with considerable economic burden and significant impact on patients’ quality of life. Despite recent advances in diabetic patient care, current clinical practice guidelines ...
Enteric pathogens modulate metabolic homeostasis in the Drosophila melanogaster host
(
Elsevier
, 2022 , Article)
On quotidian basis, living beings work out an armistice with their microbial flora and a scuffle with invading pathogens to maintain a normal state of health. Although producing virulence factors and escaping the host's ...
Metal-based nanoparticles: Promising tools for the management of cardiovascular diseases
(
Elsevier
, 2021 , Article)
Cardiovascular disease (CVD) is the leading cause of death worldwide. A search for more effective treatments of CVD is increasingly needed. Major advances in nanotechnology opened new avenues in CVD therapeutics. Owing to ...
Protein glycation – biomarkers of metabolic dysfunction and early-stage decline in health in the era of precision medicine
(
Elsevier
, 2021 , Article)
Protein glycation provides a biomarker in widespread clinical use, glycated hemoglobin HbA1c (A1C). It is a biomarker for diagnosis of diabetes and prediabetes and of medium-term glycemic control in patients with established ...
Potassium Ion Channels in Glioma: From Basic Knowledge into Therapeutic Applications
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
Ion channels, specifically those controlling the flux of potassium across cell membranes, have recently been shown to exhibit an important role in the pathophysiology of glioma, the most common primary central nervous ...
Haematological abnormalities and risk of covid-19 infection in adult patients attending primary healthcare settings
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2020 , Article)
Centres for Disease Control and prevention (CDC) reports that there are limited data and information about the impact of underlying medical conditions and the risk of infection. To date, there are no studies that report ...
mRNA-based COVID-19 Vaccines Booster Dose: BenefitRisks, and Coverage
(
Mattioli1885
, 2022 , Article)
The number of COVID-19 vaccine-rich countries that have started COVID-19 third-dose booster programs is growing dramatically despite the lack of robust evidence on the effectiveness, safety, and frequency of the required ...