Browsing College of Medicine by Title

Now showing items 495-514 of 1256

    • F-box proteins in cancer stemness: An emerging prognostic and therapeutic target 

      Abdul Q., Khan; Al-Tamimi, Maha; Uddin, Shahab; Steinhoff, Martin ( Elsevier , 2021 , Article)
      Cancer is a complex heterogenic disease with significant therapeutic challenges. The presence of cancer stem cells (CSCs) in cancer tissue orchestrates tumor growth, progression, and metastasis, the tumor heterogeneity, ...

    • Facial Nerve Palsy in Hypertriglyceridemia-Induced Pancreatitis: A Case Report and Literature Review. 

      Khalil, Sondos K; Khalil, Sulafa K; Al Refai, Fakhreddin; B Yousif, Zahra; Maliyakkal, Abdul Majeed; ... more authors ( Springer , 2023 , Article)
      Acute pancreatitis is associated with multiple local or systemic complications in response to systemic inflammation that may eventually result in multi-organ failure. Neurological complications are uncommon in acute ...

    • Factors associated with depression and anxiety in the adult population of Qatar after the first COVID-19 wave: a cross-sectional study 

      Khaled, Salma Mawfek; Amro, Iman; Bader, Lina; Woodruff, Peter; Alabdulla, Majid A.; ... more authors ( springer , 2021 , Article)
      There is limited data from Arabic-speaking countries on risk factors for depression and anxiety during the COVID-19 pandemic. Country-specific data is necessary given differences in culture, demographics, and COVID-19 ...

    • Failed immune responses across multiple pathologies share pan-tumor and circulating lymphocytic targets 

      Monette, Anne; Morou, Antigoni; Al-Banna, Nadia A.; Rousseau, Louise; Lattouf, Jean-Baptiste; ... more authors ( American Society for Clinical Investigation , 2019 , Article)
      Tumor-infiltrating lymphocytes (TILs) are widely associated with positive outcomes, yet carry key indicators of a systemic failed immune response against unresolved cancer. Cancer immunotherapies can reverse their tolerance ...

    • Fascin in Gynecological Cancers: An Update of the Literature 

      Gupta, Ishita; Vranic, Semir; Al-Thawadi, Hamda; Al Moustafa, Ala-Eddin ( MDPI , 2021 , Article)
      Fascin is an actin-binding protein that is encoded by the gene (located on chromosome 7). It triggers membrane projections and stimulates cell motility in cancer cells. Fascin overexpression has been described in different ...

    • Fatty acid-binding protein 5 (FABP5)-related signal transduction pathway in castration-resistant prostate cancer cells: a potential therapeutic target 

      Naeem, Abdulghani A.; Abdulsamad, Saud A.; Rudland, Philip S.; Malki, Mohammed I.; Ke, Youqiang ( Oxford University Press , 2019 , Article Review)
      In this short communication, a novel fatty acid-binding protein 5 (FABP5)-related signal transduction pathway in prostate cancer is reviewed. In castration-resistant prostate cancer (CRPC) cells, the FABP5-related signal ...

    • Fetal ECG extraction from maternal ECG using deeply supervised LinkNet++ model 

      Arafat, Rahman; Mahmud, Sakib; Chowdhury, Muhammad E.H.; Yalcin, Huseyin Cagatay; Khandakar, Amith; ... more authors ( Elsevier , 2023 , Article)
      Fetal heart monitoring and early disease detection using non-invasive fetal electrocardiograms (fECG) can help substantially to reduce infant death through improved diagnosis of Coronary Heart Disease (CHD) in the fetus. ...

    • Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity 

      Gupta, Vijay; Salim, Safa; Hmila, Issam; Vaikath, Nishant N.; Sudhakaran, Indulekha P.; ... more authors ( Springer Nature , 2020 , Article)
      Synucleinopathies including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA) are characterized by pathological accumulation of α-synuclein (α-syn). Amongst the various approaches ...

    • First sliding Amyand hernia harbouring appendicular schistosomiasis: Case report 

      Toffaha, Ali; El Ansari, Walid; Elaiwy, Orwa; Obaid, Munzir; Al-Yahri, Omer; ... more authors ( Elsevier Ltd , 2019 , Article)
      Introduction: Amyand's hernia (AH) is rare, schistosomiasis of the appendix is very uncommon, and both conditions coexisting together is an extremely rare event. Pre-operative diagnosis of each of the two conditions is ...

    • Five insights from the Global Burden of Disease Study 2019 

      Christopher J L, Murray; Abbafati, Cristiana; Abbas, Kaja M; Abbasi, Mohammad; Abbasi-Kangevari, Mohsen; ... more authors ( Elsevier , 2020 , Article Review)
      The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system ...

    • Flight Versus Ground Out-of-hospital Rapid Sequence Intubation Success: a Systematic Review and Meta-analysis 

      Fouche, P.F.; Stein, C.; Simpson, P.; Carlson, J.N.; Zverinova, K.M.; ... more authors ( Taylor and Francis Ltd , 2018 , Article)
      Introduction: Endotracheal intubation (ETI) is a critical procedure performed by both air medical and ground based emergency medical services (EMS). Previous work has suggested that ETI success rates are greater for air ...

    • Fluorinated Benzofuran and Dihydrobenzofuran as Anti-Inflammatory and Potential Anticancer Agents 

      Ayoub, Abeer J.; El-Achkar, Ghewa A.; Ghayad, Sandra E.; Hariss, Layal; Haidar, Razan H.; ... more authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)
      Benzofuran and 2,3-dihydrobenzofuran scaffolds are heterocycles of high value in medicinal chemistry and drug synthesis. Targeting inflammation in cancer associated with chronic inflammation is a promising therapy. In the ...

    • Follicular dendritic cells 

      Abd El-Aleem, Seham A; Saber, Entesar Ali; Aziz, Neven M; El-Sherif, Hani; Abdelraof, Asmaa M; ... more authors ( Wiley , 2021 , Article Review)
      Follicular dendritic cells (FDCs) are unique accessory immune cells that contribute to the regulation of humoral immunity. They are multitasker cells essential for the organization and maintenance of the lymphoid architecture, ...

    • Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals over 10 months 

      Salma, Younes; Nicolai, Eleonora; Al-Sadeq, Duaa W.; Younes, Nadin; Al-Dewik, Nader; ... more authors ( Elsevier , 2023 , Article)
      BackgroundEvidence on the effectiveness of vaccination-induced immunity compared to SARS-CoV-2 natural immunity is warranted to inform vaccination recommendations. AimIn this study, we aimed to conduct a comparative ...

    • Forensic utility of cranial measurements in stature reconstruction in South Africans of European descent. 

      Bidmos, Mubarak A; Adebesin, Abduljalil Adetola ( E Schweizerbart Science Publishers , 2020 , Article)
      The height of an individual (stature) is one of the biological profiles that is estimated as part of human identification process from various components of the human skeleton. The anatomical method is often used for this ...

    • Forging the Path to Precision Medicine in Qatar: A Public Health Perspective on Pharmacogenomics Initiatives 

      Bastaki, Kholoud; Velayutham, Dinesh; Irfan, Areeba; Adnan, Mohd; Mohammed, Sawsan; ... more authors ( Frontiers Media , 2024 , Article Review)
      Pharmacogenomics (PGx) is an important component of precision medicine that promises tailored treatment approaches based on an individual’s genetic information. Exploring the initiatives in research that help to integrate ...

    • A free terminal ileal perforation as the presenting sign of crohn’s disease in an adolescent female 

      Zvizdic, Z.; Zvizdic, Zlatan; Milisic, Emir; Skenderi, Faruk; Pasic, Irmina Sefic; ... more authors ( University Clinical Hospital Tuzla , 2020 , Article)
      The authors present a rare case of Aa free terminal ileal perforation as the presenting sign of Crohn's disease in an adolescent female.

    • The Freeman–Tukey double arcsine transformation for the meta-analysis of proportions: Recent criticisms were seriously misleading 

      Doi, Suhail A.; Xu, Chang ( John Wiley & Sons, Ltd , 2021 , Other)
      Pooling of proportions in meta-analysis are used to get better and more precise estimates of disease frequency, including cumulative incidence or prevalence. Meta-analysis is of course only useful when there are a limited ...

    • Frequency of adjustment with comorbidity and illness severity scores and indices in cardiac arrest research 

      Fouche, Pieter F.; Carlson, Jestin N.; Ghosh, Arindam; Zverinova, Kristina M.; Doi, Suhail A.; ... more authors ( Elsevier , 2017 , Article)
      Background Previous research demonstrates that results from observational research correlate well with results from clinical trials, and if the former are well designed these can guide clinical practice. Observational ...

    • Frequency of Parathyroid Hormone Assessment in the Evaluation of Hypercalcemia. A Comparison Between Patients With and Without a History of Malignancy in a 20-year Dataset of 20,954 Patients 

      Sheehan, M.T.; Li, Y.-H.; Doi, S.A.; Onitilo, A.A. ( SAGE Publications Ltd , 2021 , Article)
      Background: The purpose of this study was to evaluate whether a prior diagnosis of malignancy affected the assessment of parathyroid hormone (PTH) in hypercalcemic patients and whether the rate of this assessment changed ...