Browsing College of Medicine by Subject "CCL21"
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Contribution of Glycosaminoglycan binding in CCL21-mediated Migration of Breast Cancer cells
( Qatar University Press , 2021 , Poster)Lymph node metastasis constitutes a key event in Breast Cancer progression and it is a process at least partially mediated by the chemokine CCR7. Chemokine function is dependent upon their binding to both cell-surface ... -
Contribution of Heparan Sulphate Binding in CCL21-Mediated Migration of Breast Cancer Cells
( MDPI , 2022 , Article)Chemokine receptor CCR7 is implicated in the metastasis of breast cancer to the lymph nodes. Chemokine function is dependent upon their binding to both cell-surface heparan sulphate (HS) and to their specific receptors; ... -
The Role of CCL21/CCR7 Chemokine Axis in Breast Cancer Progression
( MDPI , 2015 , Article Review)Tumor-induced lymphangiogenesis facilitates breast cancer progression by generating new lymphatic vessels that serve as conduits for tumor dissemination to lymph nodes and beyond. Given the recent evidence suggesting the ...