Browsing College of Medicine by Subject "Raynaud's phenomenon"
Now showing items 1-2 of 2
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Estrogen receptor and the gender bias in Raynaud's phenomenon.
( Bentham Science Publishers , 2023 , Other)Cold-induced vasoconstriction is a normal physiological reaction aiming at redirecting blood into internal more vital body organs [1]. It is mediated by sympathetic release of norepinephrine as well as by local effectors ... -
GPER Acts Through the cAMP/Epac/JNK/AP-1 Pathway to Induce Transcription of Alpha 2C Adrenoceptor in Human Microvascular Smooth Muscle Cells
( Wolters Kluwer Health , 2023 , Article)Raynaud's phenomenon, which results from exaggerated cold-induced vasoconstriction, is more prevalent in females than males. We previously showed that estrogen increases the expression of alpha 2C-adrenoceptors (α2C-AR), ...