تصفح College of Pharmacy حسب المؤلف "Khan, Abdul Q."
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Epigenetic inhibitors and their role in cancer therapy
Abdelaziz, Nouha; Therachiyil, Lubna; Sadida, Hana Q.; Ali, Ateeque Mohamed; Khan, Omar S.; Singh, Mayank; Khan, Abdul Q.; Akil, Ammira S.Al Shabeeb; Bhat, Ajaz A.; Uddin, Shahab... more authors ... less authors ( Elsevier , 2023 , Article)Epigenetic modifications to DNA are crucial for normal cellular and biological functioning. DNA methylation, histone modifications, and chromatin remodeling are the most common epigenetic mechanisms. These changes are ... -
Shrinking the battlefield in cancer therapy: Nanotechnology against cancer stem cells
Queenie, Fernandes; Therachiyil, Lubna; Khan, Abdul Q.; Bedhiafi, Takwa; Korashy, Hesham M; Bhat, Ajaz A.; Uddin, Shahab... more authors ... less authors ( Elsevier , 2023 , Article)Cancer remains one of the leading causes of mortality worldwide, presenting a significant healthcare challenge owing to the limited efficacy of current treatments. The application of nanotechnology in cancer treatment ... -
Thiostrepton inhibits growth and induces apoptosis by targeting FoxM1/SKP2/MTH1 axis in B-precursor acute lymphoblastic leukemia cells
Kuttikrishnan, Shilpa; Prabhu, Kirti S.; Khan, Abdul Q.; Alali, Feras Q.; Ahmad, Aamir; Uddin, Shahab... more authors ... less authors ( Taylor and Francis Group , 2021 , Article)Forkhead box M1 (FoxM1) is a transcription factor that plays an important role in the etiology of many cancers, however, its role has not been elucidated in B-precursor acute lymphoblastic leukemia (B-pre-ALL). In the ...